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Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in heme biosynthesis; deficiency in the human homolog can result in the disease congenital erythropoietic porphyria
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YOR278W
    below threshold
    18.76
  • N' NOP1pr-GFP in SD
    YOR278W
    cytosol
    123.77
  • N' TEF2pr-mCherry in SD
    YOR278W
    cytosol
    195.696
  • N' NATIVEpr-GFP in SD
    YOR278W
    cytosol
    21.1972
  • N' TEF2pr-VC and Cyto-VN in SD
    YOR278W
    cytosol
    55.6955
  • C’ GFP library in SD+DTT 
    YOR278W
    cytosol
    21.45
    1.14
    No
  • C’ GFP library in SD+H2O2
    YOR278W
    cytosol
    21.22
    1.13
    No
  • C’ GFP library in Starvation Media
    YOR278W
    cytosol
    17.57
    0.93
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    below threshold
  • C’ GFP library on the background of CCT mutant
    noimage.png
    below threshold
    21.7829
    1.16064
    No