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Protein that negatively regulates the SCF E3-ubiquitin ligase by interacting with and preventing neddyation of the cullin subunit, Cdc53p; longevity determinant that is preferentially expressed in young cells; similar to mammalian Cand1
Localization:
Intensity:
Fold change:
Significance:
  • C’ GFP library in SD
    YOL025W
    below threshold
    17.26
  • N' NOP1pr-GFP in SD
    YOL025W
    cytosol,nucleus
    61.3316
  • N' TEF2pr-mCherry in SD
    YOL025W
    nucleus
    82.3398
  • N' NATIVEpr-GFP in SD
    YOL025W
    below threshold
    27.2789
  • N' TEF2pr-VC and Cyto-VN in SD
    noimage.png
    #N/A
    0
  • C’ GFP library in SD+DTT 
    YOL025W
    cytosol
    15.26
    0.88
    No
  • C’ GFP library in SD+H2O2
    YOL025W
    cytosol
    20.57
    1.19
    No
  • C’ GFP library in Starvation Media
    YOL025W
    cytosol
    15.37
    0.88
    No
  • C’ GFP library on the background of Pup2-DaMP
    noimage.png
    below threshold
  • C’ GFP library on the background of CCT mutant
    noimage.png
    below threshold
    18.5516
    1.07411
    No