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Protein that negatively regulates the SCF E3-ubiquitin ligase by interacting with and preventing neddyation of the cullin subunit, Cdc53p; longevity determinant that is preferentially expressed in young cells; similar to mammalian Cand1
Localization:
Intensity:
Fold change:
Significance:
-
C’ GFP library in SD
below threshold17.26 -
N' NOP1pr-GFP in SD
cytosol,nucleus61.3316 -
N' TEF2pr-mCherry in SD
nucleus82.3398 -
N' NATIVEpr-GFP in SD
below threshold27.2789 -
N' TEF2pr-VC and Cyto-VN in SD
#N/A0 -
C’ GFP library in SD+DTT
cytosol15.260.88No -
C’ GFP library in SD+H2O2
cytosol20.571.19No -
C’ GFP library in Starvation Media
cytosol15.370.88No -
C’ GFP library on the background of Pup2-DaMP
below threshold -
C’ GFP library on the background of CCT mutant
below threshold18.55161.07411No