Proteopedia is a collaborative, 3D web-encyclopedia of protein, nucleic acid and otherbiomolecule structures. Created as a means for communicating biomolecule structures to a diverse scientific audience, Proteopedia presents structural annotation in an intuitive, interactive format and allows members of the scientific community to easily contribute their own annotations. There are ~125,000 pages in Proteopedia contributed by more than 3,300 users from over ~55 countries worldwide, with many pages translated into over a dozen different languages.