Publications

  1. Goldin-Azulay K., Fraiberg M., Trofimyuk O., Levin Y., Reuven N., Kopitman E. & Elazar Z. (2024). Multiplex genomic tagging of mammalian ATG8s to study autophagy.  Journal of Biological Chemistry. 2024 Dec , 300 (12).
  2. Shatz O. & Elazar Z. (2024). The physiological relevance of autophagosome morphogenesis.  Trends in Biochemical Sciences. 2024 May , 49 (7):569-572.
  3. Isola D. & Elazar Z. (2024). Phospholipid Supply for Autophagosome Biogenesis.  Journal of Molecular Biology. 2024 Jun , 436 (15).
  4. Shatz O., Fraiberg M., Isola D., Das S., Gogoi O., Polyansky A., Shimoni E., Dadosh T., Dezorella N., Wolf S. G. & Elazar Z. (2024). Rim aperture of yeast autophagic membranes balances cargo inclusion with vesicle maturation.  Developmental Cell. 2024 Mar , 59 (7):911-923.e4.
  5. Cuervo A. M., Elazar Z., Evans C., Ge L., Hansen M., Jäättelä M., Liang J. R., Loos B., Mizushima N., Simon A. K., Tooze S., Yoshimori T. & Nakamura S. (2024). Next questions in autophagy.  Nature Cell Biology. 2024 Apr , 26 (5):661-666.
  6. Shatz O. & Elazar Z. (2024). Autophagy in a Nutshell.  FEBS Letters. 2024 Jan , 598 (1):7-8.
  7. Terradas A. L., Zittlau K. I., Macek B., Fraiberg M., Elazar Z. & Kahle P. J. (2023). Correction: Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications (Journal of Biological Chemistry (2021) 297(5), (S0021925821011455), (10.1016/j.jbc.2021.101339)).  Journal of Biological Chemistry. 2023 Aug , 299 (8).
  8. Nalbach K., Schifferer M., Bhattacharya D., Ho-Xuan H., Tseng W. C., Williams L. A., Stolz A., Lichtenthaler S. F., Elazar Z. & Behrends C. (2023). Author Correction: Spatial proteomics reveals secretory pathway disturbances caused by neuropathy-associated TECPR2 (Nature Communications, (2023), 14, 1, (870), 10.1038/s41467-023-36553-6).  Nature Communications. 2023 Dec , 14 (1).
  9. Nalbach K., Schifferer M., Bhattacharya D., Ho-Xuan H., Tseng W., Williams L. A., Stolz A., Lichtenthaler S. F., Elazar Z. & Behrends C. (2023). Spatial proteomics reveals secretory pathway disturbances caused by neuropathy-associated TECPR2.  Nature Communications. 2023 Dec , 14 (1).
  10. Reggiori F., Boya P., da Costa D., Elazar Z., Eskelinen E., Farrés J., Guettler S., Kraft C., Jungbluth H., Martinez A., Morel E., Pless O., Proikas-Cezanne T. & Simonsen A. (2022). The mechanism of macroautophagy: The movie.  Autophagy Reports. 2022 Dec , 1 (1):414-417.
  11. Polyansky A., Shatz O., Fraiberg M., Shimoni E., Dadosh T., Mari M., Reggiori F. M., Qin C., Han X. & Elazar Z. (2022). Phospholipid imbalance impairs autophagosome completion.  EMBO Journal. 2022 Dec , 41 (23).
  12. Mukherjee S., Maddalena M., Lü Y., Martinez S., Nataraj N. B., Noronha A., Sinha S., Teng K., Cohen-Kaplan V., Ziv T., Arandkar S., Hassin O., Chatterjee R., Pirona A., Shreberk-Shaked M., Gershoni A., Aylon Y., Elazar Z., Yarden Y., Schramek D. & Oren M. (2022). Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins.  Proceedings of the National Academy of Sciences. 2022 Apr , 119 (17).
  13. Lechado Terradas A., Zittlau K., Macek B., Fraiberg M., Elazar Z. & Kahle P. J. (2021). Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications.  Journal of Biological Chemistry. 2021 Nov , 297 (5).
  14. Shatz O., Fraiberg M. & Elazar Z. (2021). Atg1 kinase activity links PAS dissolution to balanced Atg8 conjugation.  Trends in Cell Biology. 2021 Dec , 32 (3).
  15. Klionsky D. J., Petroni G., Amaravadi R. K., Baehrecke E. H., Ballabio A., Boya P., Bravo-San Pedro J. M., Cadwell K., Cecconi F., Choi A. M., Choi M. E., Chu C. T., Codogno P., Colombo M., Cuervo A. M., Deretic V., Dikic I., Elazar Z., Eskelinen E. L., Fimia G. M., Gewirtz D. A., Green D. R., Hansen M., Jäättelä M., Johansen T., Juhász G., Karantza V., Kraft C., Kroemer G., Ktistakis N. T., Kumar S., Lopez-Otin C., Macleod K. F., Madeo F., Martinez J., Meléndez A., Mizushima N., Münz C., Penninger J. M., Perera R., Piacentini M., Reggiori F., Rubinsztein D. C., Ryan K., Sadoshima J., Santambrogio L., Scorrano L., Simon H. U., Simon A. K., Simonsen A., Stolz A., Tavernarakis N., Tooze S. A., Yoshimori T., Yuan J., Yue Z., Zhong Q., Galluzzi L. & Pietrocola F. (2021). Autophagy in major human diseases.  EMBO Journal. 2021 Oct , 40 (19).
  16. Teresak P., Lapao A., Subic N., Boya P., Elazar Z. & Simonsen A. (2021). Regulation of PRKN-independent mitophagy.  Autophagy. 2021 Feb , 18 (1):24-39.
  17. Tamim-Yecheskel B., Fraiberg M., Kokabi K., Freud S., Shatz O., Marvaldi L., Subic N., Brenner O., Tsoory M., Eilam-Altstadter R., Biton I., Savidor A., Dezorella N., Heimer G., Behrends C., Ben-Zeev B. & Elazar Z. (2021). A tecpr2 knockout mouse exhibits age-dependent neuroaxonal dystrophy associated with autophagosome accumulation.  Autophagy. 2021, 17 (10):3082-3095.
  18. Fraiberg M. & Elazar Z. (2020). Genetic defects of autophagy linked to disease.  . 2020, :293-323.
  19. Fraiberg M., Tamim-Yecheskel B., Kokabi K., Subic N., Heimer G., Eck F., Nalbach K., Behrends C., Ben-Zeev B., Shatz O. & Elazar Z. (2020). Lysosomal targeting of autophagosomes by the TECPR domain of TECPR2.  Autophagy. 2020 Nov , :1-13.
  20. Fraiberg M. & Elazar Z. (2020). Selective autophagy bears bone.  EMBO Journal. 2020 Sept , 39 (17).
  21. Polyansky A., Shatz O. & Elazar Z. (2020). De Novo Phospholipid Synthesis Promotes Efficient Autophagy.  Biochemistry. 2020 Mar , 59 (9):1011-1012.
  22. Kraft C., Boya P., Codogno P., Elazar Z., Eskelinen E., Farres J., Kirkin V., Jungbluth H., Martinez A., Pless O., Primard C., Proikas-Cezanne T., Simonsen A. & Reggiori F. (2019). Driving next-generation autophagy researchers towards translation (DRIVE), an international PhD training program on autophagy.  Autophagy. 2019 Feb , 15 (2):347-351.
  23. Deretic V., Prossnitz E., Burge M., Campen M. J., Cannon J., Liu K. J., Liu M., Hall P., Sklar L. A., Allers L., Mariscal L., Garcia S. A., Weaver J., Baehrecke E. H., Behrends C., Cecconi F., Codogno P., Chen G., Elazar Z., Eskelinen E., Fourie B., Gozuacik D., Hong W., Jo E., Johansen T., Juhasz G., Kimch A., Ktistakis N., Kroemer G., Mizushima N., Muenz C., Reggiori F., Rubinsztein D., Ryan K., Schroder K., Shen H., Simonsen A., Tooze S. A., Vaccaro M., Yoshimori T., Yu L., Zhang H. & Klionsky D. J. (2019). Autophagy, Inflammation, and Metabolism (AIM) Center in its second year.  Autophagy. 2019 Jul , 15 (10):1829-1833.
  24. Shatz O. & Elazar Z. (2019). ATG9 raises the BAR for PI4P in autophagy.  Journal of Cell Biology. 2019 Apr , 218 (5):1432-1433.
  25. Dikic I. & Elazar Z. (2018). Mechanism and medical implications of mammalian autophagy.  Nature Reviews Molecular Cell Biology. 2018 Jun , 19 (6):349-364.
  26. Winer H., Fraiberg M., Abada A., Dadosh T., Tamim-Yecheskel B. & Elazar Z. (2018). Autophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins.  Nature Communications. 2018 Sept , 9 .
  27. Demishtein A., Fraiberg M., Berko D., Tirosh B., Elazar Z. & Navon A. (2017). SQSTM1/p62-mediated autophagy compensates for loss of proteasome polyubiquitin recruiting capacity.  Autophagy. 2017 Aug , 13 (10):1697-1708.
  28. Schmukler E., Wolfson E., Elazar Z., Kloog Y. & Pinkas-Kramarski R. (2017). Continuous treatment with FTS confers resistance to apoptosis and affects autophagy.  PLoS ONE. 2017 Feb , 12 (2).
  29. Abada A., Levin-Zaidman S., Porat Z., Dadosh T. & Elazar Z. (2017). SNARE priming is essential for maturation of autophagosomes but not for their formation.  Proceedings of the National Academy of Sciences of the United States of America. 2017 Nov , 114 (48):12749-12754.
  30. Klionsky D. J., Abdelmohsen K., Abe A., Abedin M. J., Abeliovich H., Arozena A. A., Adachi H., Adams C. M., Adams P. D., Adeli K., Adhihetty P. J., Adler S. G., Agam G., Agarwal R., Aghi M. K., Agnello M., Agostinis P., Aguilar P. V., Aguirre-Ghiso J., Airoldi E. M., Ait-Si-Ali S., Akematsu T., Akporiaye E. T., Al-Rubeai M., Albaiceta G. M., Albanese C., Albani D., Albert M. L., Aldudo J., Alguel H., Alirezaei M., Alloza I., Almasan A., Almonte-Beceril M., Alnemri E. S., Alonso C., Altan-Bonnet N., Altieri D. C., Alvarez S., Alvarez-Erviti L., Alves S., Arama E., Eisenberg-Lerner A., Elazar Z., Galili G. & Kimchi A. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).  Autophagy. 2016 Jan , 12 (1):1-222.
  31. Fraiberg M. & Elazar Z. (2016). A TRIM16-Galactin3 Complex Mediates Autophagy of Damaged Endomembranes.  Developmental Cell. 2016 Oct , 39 (1):1-2.
  32. Somekh J., Peleg M., Eran A., Koren I., Feiglin A., Demishtein A., Shiloh R., Heiner M., Kong S., Elazar Z. & Kohane I. (2016). A model-driven methodology for exploring complex disease comorbidities applied to autism spectrum disorder and inflammatory bowel disease.  Journal of Biomedical Informatics. 2016 Oct , 63 :366-378.
  33. Shatz O., Holland P., Elazar Z. & Simonsen A. (2016). Complex Relations Between Phospholipids, Autophagy, and Neutral Lipids.  Trends in Biochemical Sciences. 2016 Nov , 41 (11):907-923.
  34. Shpilka T., Welter E., Borovsky N., Amar N., Shimron F., Peleg Y. & Elazar Z. (2015). Fatty acid synthase is preferentially degraded by autophagy upon nitrogen starvation in yeast.  Proceedings of the National Academy of Sciences of the United States of America. 2015 Feb , 112 (5):1434-1439.
  35. Shpilka T., Welter E., Borovsky N., Amar N., Mari M., Reggiori F. & Elazar Z. (2015). Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis.  The EMBO Journal. 2015 Aug , 34 (16):2117-2131.
  36. Demishtein A., Porat Z., Elazar Z. & Shvets E. (2015). Applications of flow cytometry for measurement of autophagy.  Methods. 2015 Mar , 75 :87-95.
  37. Stadel D., Millarte V., Tillmann K. D., Huber J., Tamin - Yecheskel -. Y. B., Akutsu M., Demishtein A., Ben-Zeev B., Anikster Y., Perez F., Doetsch V., Elazar Z., Rogov V., Farhan H. & Behrends C. (2015). TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export.  Molecular Cell. 2015 Oct , 60 (1):89-104.
  38. Gelman A., Rawet Slobodkin S. M. & Elazar Z. (2015). Huntingtin facilitates selective autophagy.  Nature Cell Biology. 2015 Mar , 17 (3):214-215.
  39. Welter E. & Elazar Z. (2015). Autophagy mediates nonselective RNA degradation in starving yeast.  EMBO Journal. 2015 Jan , 34 (2):131-133.
  40. Rawet-Slobodkin M. & Elazar Z. (2015). PLEKHM1: A multiprotein adaptor for the endolysosomal system.  Molecular Cell. 2015 Jan , 57 (1):1-3.
  41. Shpilkay T. & Elazar Z. (2015). Lipid droplets regulate autophagosome biogenesis.  Autophagy. 2015 Jan , 11 (11):2130-2131.
  42. Abada A. & Elazar Z. (2014). Getting ready for building: signaling and autophagosome biogenesis.  EMBO Reports. 2014 Aug , 15 (8):839-852.
  43. Tooze S. A., Abada A. & Elazar Z. (2014). Endocytosis and Autophagy: exploitation or cooperation?.  Cold Spring Harbor perspectives in biology. 2014 May , 6 (5).
  44. Politi Y., Gal L., Kalifa Y., Ravid L., Elazar Z. & Arama E. (2014). Paternal mitochondrial destruction after fertilization is mediated by a common endocytic and autophagic pathway in drosophila.  Developmental Cell. 2014 May , 29 (3):305-320.
  45. Slobodkin M. R. & Elazar Z. (2013). The Atg8 family: multifunctional ubiquitin-like key regulators of autophagy.  . 2013, :51-64.
  46. Rawet-Slobodkin M. & Elazar Z. (2013). 8-Nitro-cGMP-A new player in antibacterial autophagy.  Molecular Cell. 2013 Dec , 52 (6):767-768.
  47. Oz-Levi D., Gelman A., Elazar Z. & Lancet D. (2013). TECPR2:A new autophagy link for neurodegeneration.  Autophagy. 2013 May , 9 (5):801-802.
  48. Berryman S., Brooks E., Burman A., Hawes P., Roberts R., Netherton C., Monaghan P., Whelband M., Cottam E., Elazar Z., Jackson T. & Wileman T. (2012). Foot-and-mouth disease virus induces autophagosomes during cell entry via a class III phosphatidylinositol 3-kinase-independent pathway.  Journal of Virology. 2012 Dec , 86 (23):12940-12953.
  49. Shpilka T., Mizushima N. & Elazar Z. (2012). Ubiquitin-like proteins and autophagy at a glance.  Journal of Cell Science. 2012, 125 (10):2343-2348.
  50. Oz Levi D., Ben-Zeev B., Ruzzo E. K., Hitomi Y., Gelman A., Pelak K., Anikster Y., Reznik-Wolf H., Bar-Joseph I., Olender T., Alkelai A., Weiss M., Ben-Asher E., Ge D., Shianna K. V., Elazar Z., Goldstein D. B., Pras E. & Lancet D. (2012). Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis.  American Journal of Human Genetics. 2012 Dec , 91 (6):1065-1072.
  51. Klionsky D. J., Elazar Z., Abdalla F. C., Abeliovich H., Abraham R. T., Acevedo-Arozena A., Adeli K., Agholme L., Agnello M., Agostinis P., Aguirre-Ghiso J. A., Ahn H. J., Ait-Mohamed O., Ait-Si-Ali S., Akematsu T., Akira S., Al-Younes H. M., Al-Zeer M. A., Albert M. L. & Albin R. L. (2012). Guidelines for the use and interpretation of assays for monitoring autophagy.  Autophagy. 2012 Apr , 8 (4):445-544.
  52. Rubinsztein D. C., Shpilka T. & Elazar Z. (2012). Mechanisms of autophagosome biogenesis.  Current Biology. 2012 Jan , 22 (1):R29-R34.
  53. Shpilka T. & Elazar Z. (2012). Essential Role for the Mammalian ATG8 Isoform LC3C in Xenophagy.  Molecular Cell. 2012 Nov , 48 (3):325-326.
  54. Weidberg H., Shpilka T., Shvets E., Abada A., Shimron F. & Elazar Z. (2011). LC3 and GATE-16 N termini mediate membrane fusion processes required for autophagosome biogenesis.  Developmental Cell. 2011 Apr , 20 (4):444-54.
  55. Shpilka T., Weidberg H., Pietrokovski S. & Elazar Z. (2011). Atg8: An autophagy-related ubiquitin-like protein family.  GENOME BIOLOGY. 2011 Jul , 12 (7).
  56. Weidberg H. & Elazar Z. (2011). TBK1 mediates crosstalk between the innate immune response and autophagy.  Science Signaling. 2011 Aug , 4 (187).
  57. Scherz-Shouval R. & Elazar Z. (2011). Regulation of autophagy by ROS: Physiology and pathology.  Trends in Biochemical Sciences. 2011 Jan , 36 (1):30-38.
  58. Weidberg H., Shvets E. & Elazar Z. (2011). Biogenesis and Cargo Selectivity of Autophagosomes.  Annual Review of Biochemistry. 2011, :125-156.
  59. Klionsky D. J., Baehrecke E. H., Brumell J. H., Chu C. T., Codogno P., Cuervo A. M., Debnath J., Deretic V., Elazar Z., Eskelinen E., Finkbeiner S., Fueyo-Margareto J., Gewirtz D., Jaattela M., Kroemer G., Levine B., Melia T. J., Mizushima N. & Rubinsztein D. C. (2011). A comprehensive glossary of autophagy-related molecules and processes (2nd edition).  Autophagy. 2011 Nov , 7 (11):1273-1294.
  60. Kovsan J., Blueher M., Tarnovscki T., Kloeting N., Kirshtein B., Madar L., Shai I., Golan R., Harman-Boehm I., Schoen M. R., Greenberg A. S., Elazar Z., Bashan N. & Rudich A. (2011). Altered autophagy in human adipose tissues in obesity.  Journal Of Clinical Endocrinology & Metabolism. 2011 Feb , 96 (2):E268-E277.
  61. Levine B. & Elazar Z. (2011). Inheriting maternal mtDNA.  Science. 2011 Nov , 334 (6059):1069-1070.
  62. Gelman A. & Elazar Z. (2011). Autophagic factors cut to the bone.  Developmental Cell. 2011 Nov , 21 (5):808-810.
  63. Kario E., Amar N., Elazar Z. & Navon A. (2011). A new autophagy-related checkpoint in the degradation of an ERAD-M target.  Journal of Biological Chemistry. 2011 Apr , 286 (13):11479-11491.
  64. Shpilka T. & Elazar Z. (2011). Shedding Light on Mammalian Microautophagy.  Developmental Cell. 2011 Jan , 20 (1):1-2.
  65. Shvets E., Abada A., Weidberg H. & Elazar Z. (2011). Dissecting the involvement of LC3B and GATE-16 in p62 recruitment into autophagosomes.  Autophagy. 2011 Jul , 7 (7):683-688.
  66. Weidberg H., Shvets E., Shpilka T., Shimron F., Shinder V. & Elazar Z. (2010). LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis.  EMBO Journal. 2010 Jun , 29 (11):1792-1802.
  67. Klionsky D. J., Codogno P., Cuervo A. M., Deretic V., Elazar Z., Fueyo-Margareto J., Gewirtz D. A., Kroemer G., Levine B., Mizushima N., Rubinsztein D. C., Thumm M. & Tooze S. A. (2010). A comprehensive glossary of autophagy-related molecules and processes.  Autophagy. 2010 May , 6 (4):438-448.
  68. Scherz-Shouval R., Weidberg H., Gonen C., Wilder S., Elazar Z. & Oren M. (2010). p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.  Proceedings of the National Academy of Sciences of the United States of America. 2010 Oct , 107 (43):18511-18516.
  69. Weidberg H., Shpilka T., Shvets E. & Elazar Z. (2010). Mammalian Atg8s: One is simply not enough.  Autophagy. 2010 Aug , 6 (6):808-809.
  70. Weidberg H., Shvets E. & Elazar Z. (2009). Lipophagy: Selective Catabolism Designed for Lipids.  Developmental Cell. 2009 May , 16 (5):628-630.
  71. Kirkin V., Lamark T., Sou Y. S., Bjørkøy G., Nunn J. L., Bruun J. A., Shvets E., McEwan D. G., Clausen T. H., Wild P., Bilusic I., Theurillat J. P., Øvervatn A., Ishii T., Elazar Z., Komatsu M., Dikic I. & Johansen T. (2009). A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates.  Molecular Cell. 2009 Feb , 33 (4):505-516.
  72. Scherz-Shouval R. & Elazar Z. (2009). MONITORING STARVATION-INDUCED REACTIVE OXYGEN SPECIES FORMATION.  . 2009, :119-130.
  73. Shvets E. & Elazar Z. (2009). FLOW CYTOMETRIC ANALYSIS OF AUTOPHAGY IN LIVING MAMMALIAN CELLS.  . 2009, :131-141.
  74. Klionsky D. J., Abeliovich H., Agostinis P., Agrawal D. K., Aliev G., Askew D. S., Baba M., Baehrecke E. H., Bahr B. A., Ballabio A., Bamber B. A., Bassham D. C., Bergamini E., Bi X., Biard-Piechaczyk M., Blum J. S., Bredesen D. E., Brodsky J. L., Brumell J. H., Brunk U. T., Bursch W., Camougrand N., Cebollero E., Cecconi F., Chen Y., Chin L. S., Choi A., Chu C. T., Chung J., Clarke P. G., Clark R. S., Clarke S. G., Clavé C., Cleveland J. L., Codogno P., Colombo M. I., Cotomontes A., Cregg J. M., Cuervo A. M., Debnath J., Demarchi F., Dennis P. B., Dennis P. A., Deretic V., Devenish R. J., Di Sano F., Dice J. F., DiFiglia M., Dinesh-Kumar S., Distelhorst C. W., Djavaheri-Mergny M., Dorsey F. C., Dröge W., Dron M., Dunn W. A., Duszenko M., Eissa N. T., Elazar Z., Esclatine A., Eskelinen E. L., Fésüs L., Finley K. D., Fuentes J. M., Fueyo J., Fujisaki K., Galliot B., Gao F. B., Gewirtz D. A., Gibson S. B., Gohla A., Goldberg A. L., Gonzalez R., González-Estévez C., Gorski S., Gottlieb R. A., Häussinger D., He Y. W., Heidenreich K., Hill J. A., Høyer-Hansen M., Hu X., Huang W. P., Iwasaki A., Jäättelä M., Jackson W. T., Jiang X., Jin S., Johansen T., Jung J. U., Kadowaki M., Kang C., Kelekar A., Kessel D. H., Kiel J. A., Hong P. K., Kimchi A., Kinsella T. J., Kiselyov K., Kitamoto K., Knecht E., Komatsu M., Kominami E., Kondo S., Kovács A. L., Kroemer G., Kuan C. Y., Kumar R., Kundu M., Landry J., Laporte M., Le W., Lei H. Y., Lenardo M. J., Levine B., Lieberman A., Lim K. L., Lin F. C., Liou W., Liu L. F., Lopez-Berestein G., López-Otín C., Lu B., Macleod K. F., Malorni W., Martinet W., Matsuoka K., Mautner J., Meijer A. J., Meléndez A., Michels P., Miotto G., Mistiaen W. P., Mizushima N., Mograbi B., Monastyrska I., Moore M. N., Moreira P. I., Moriyasu Y., Motyl T., Münz C., Murphy L. O., Naqvi N. I., Neufeld T. P., Nishino I., Nixon R. A., Noda T., Nürnberg B., Ogawa M., Oleinick N. L., Olsen L. J., Ozpolat B., Paglin S., Palmer G. E., Papassideri I., Parkes M., Perlmutter D. H., Perry G., Piacentini M., Pinkas-Kramarski R., Prescott M., Proikascezanne T., Raben N., Rami A., Reggiori F., Rohrer B., Rubinsztein D. C., Ryan K. M., Sadoshima J., Sakagami H., Sakai Y., Sandri M., Sasakawa C., Sass M., Schneider C., Seglen P. O., Seleverstov O., Settleman J., Shacka J. J., Shapiro I. M., Sibirny A., Silva-Zacarin E. C., Simon H. U., Simone C., Simonsen A., Smith M. A., Spanel-Borowski K., Srinivas V., Steeves M., Stenmark H., Stromhaug P. E., Subauste C. S., Sugimoto S., Sulzer D., Suzuki T., Swanson M. S., Tabas I., Takeshita F., Talbot N. J., Tallóczy Z., Tanaka K., Tanaka K., Tanida I., Taylor G. S., Taylor J. P., Terman A., Tettamanti G., Thompson C. B., Thumm M., Tolkovsky A. M., Tooze S. A., Truant R., Tumanovska L. V., Uchiyama Y., Ueno T., Uzcátegui N. L., Van Der Klei I., Vaquero E. C., Vellai T., Vogel M. W., Wang H. G., Webster P., Wiley J. W., Xi Z., Xiao G., Yahalom J., Yang J. M., Yap G., Yin X. M., Yoshimori T., Yu L., Yue Z., Yuzaki M., Zabirnyk O., Zheng X., Zhu X. & Deter R. L. (2008). Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.  Autophagy. 2008 Feb , 4 (2):151-175.
  75. Shvets E., Fass E., Scherz-Shouval R. & Elazar Z. (2008). The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes.  Journal of Cell Science. 2008 Aug , 121 (16):2685-2695.
  76. Shvets E., Fass E. & Elazar Z. (2008). Utilizing flow cytometry to monitor autophagy in living mammalian cells.  Autophagy. 2008 Jul , 4 (5):621-628.
  77. Klionsky D. J., Elazar Z., Seglen P. O. & Rubinsztein D. C. (2008). Does bafilomycin A1 block the fusion of autophagosomes with lysosomes?.  Autophagy. 2008 Oct , 4 (7):849-850.
  78. Shvets E. & Elazar Z. (2008). Autophagy-independent incorporation of GFP-LC3 into protein aggregates is dependent on its interaction with p62/SQSTM1.  Autophagy. 2008 Nov , 4 (8):1054-1056.
  79. Scherz-Shouval R., Shvets E. & Elazar Z. (2007). Oxidation as a post-translational modification that regulates autophagy.  Autophagy. 2007, 3 (4):371-373.
  80. Scherz-Shouval R. & Elazar Z. (2007). ROS, mitochondria and the regulation of autophagy.  Trends in Cell Biology. 2007 Sept , 17 (9):422-427.
  81. Scherz-Shouval R., Shvets E., Fass E., Shorer H., Gil L. & Elazar Z. (2007). Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4.  EMBO Journal. 2007 Apr , 26 (7):1749-1760.
  82. Fass E., Amar N. & Elazar Z. (2007). Identification of essential residues for the C-terminal cleavage of the mammalian LC3: A lesson from yeast Atg8.  Autophagy. 2007, 3 (1):48-50.
  83. Amar N., Lustig G., Ichimura Y., Ohsumi Y. & Elazar Z. (2006). Two newly identified sites in the ubiquitin-like protein Atg8 are essential for autophagy.  EMBO Reports. 2006 Jun , 7 (6):635-642.
  84. Fass E., Shvets E., Degani I., Hirschberg K. & Elazar Z. (2006). Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes.  Journal of Biological Chemistry. 2006 Nov , 281 (47):36303-36316.
  85. Slavikova S., Shy G., Yao Y., Giozman R., Levanony H., Pietrokovski S., Elazar Z. & Galili G. (2005). The autophagy-associated Atg8 gene family operates both under favourable growth conditions and under starvation stresses in Arabidopsis plants.  Journal of Experimental Botany. 2005 Nov , 56 (421):2839-2849.
  86. Shorer H., Amar N., Meerson A. & Elazar Z. (2005). Modulation of N-ethylmaleimide-sensitive factor activity upon amino acid deprivation.  Journal of Biological Chemistry. 2005 Apr , 280 (16):16219-16226.
  87. O'Sullivan G., Kneussel M., Elazar Z. & Betz H. (2005). GABARAP is not essential for GABAA receptor targeting to the synapse.  European Journal of Neuroscience. 2005 Nov , 22 (10):2644-2648.
  88. Barzilay E., Ben-Califa N., Supino-Rosin L., Kashman Y., Hirschberg K., Elazar Z. & Neumann D. (2004). Geldanamycin-associated Inhibition of Intracellular Trafficking Is Attributed to a Co-purified Activity.  Journal of Biological Chemistry. 2004 Feb , 279 (8):6847-6852.
  89. Conticello S., Kowalsman N., Jacobsen C., Yudkovsky G., Sato K., Elazar Z., Petersen C., Aronheim A. & Fainzilber M. (2003). The prodomain of a secreted hydrophobic mini-protein facilitates its export from the endoplasmic reticulum by hitchhiking on sorting receptors.  Journal of Biological Chemistry. 2003 Jul , 278 (29):26311-26314.
  90. Elazar Z., Scherz-Shouval R. & Shorer H. (2003). Involvement of LMA1 and GATE-16 family members in intracellular membrane dynamics.  Biochimica et Biophysica Acta - Molecular Cell Research. 2003 Aug , 1641 (2-3):145-156.
  91. Stuven E., Porat A., Shimron F., Fass E., Kaloyanova D., Brugger B., Wieland F., Elazar Z. & Helms J. (2003). Intra-Golgi protein transport depends on a cholesterol balance in the lipid membrane.  Journal of Biological Chemistry. 2003 Dec , 278 (52):53112-53122.
  92. Scherz-Shouval R., Sagiv Y., Shorer H. & Elazar Z. (2003). The COOH terminus of GATE-16, an intra-golgi transport modulator, is cleaved by the human cysteine protease HsApg4A.  Journal of Biological Chemistry. 2003 Apr , 278 (16):14053-14058.
  93. Muller J., Shorter J., Newman R., Deinhardt K., Sagiv Y., Elazar Z., Warren G. & Shima D. (2002). Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion.  Journal of Cell Biology. 2002 Jun , 157 (7):1161-1173.
  94. Sagiv Y., Legesse-Miller A., Porat A. & Elazar Z. (2000). GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28.  EMBO Journal. 2000 Apr , 19 (7):1494-1504.
  95. Supino-Rosin L., Yoshimura A., Yarden Y., Elazar Z. & Neumann D. (2000). Intracellular retention and degradation of the epidermal growth factor receptor, Two distinct processes mediated by benzoquinone ansamycins.  Journal of Biological Chemistry. 2000 Jul , 275 (29):21850-21855.
  96. Porat A., Sagiv Y. & Elazar Z. (2000). A 56-kDa selenium-binding protein participates in intra-Golgi protein transport.  Journal of Biological Chemistry. 2000 May , 275 (19):14457-14465.
  97. Porat A. & Elazar Z. (2000). Regulation of intra-Golgi membrane transport by calcium.  Journal of Biological Chemistry. 2000 Sept , 275 (38):29233-29237.
  98. Paz Y., Elazar Z. & Fass D. (2000). Structure of GATE-16, membrane transport modulator and mammalian ortholog of autophagocytosis factor Aut7p.  Journal of Biological Chemistry. 2000 Aug , 275 (33):25445-25450.
  99. Legesse-Miller A., Sagiv Y., Glozman R. & Elazar Z. (2000). Aut7p, a soluble autophagic factor, participates in multiple membrane trafficking processes.  Journal of Biological Chemistry. 2000 Oct , 275 (42):32966-32973.
  100. Soussan L., Burakov D., Daniels M., Toister-Achituv M., Porat A., Yarden Y. & Elazar Z. (1999). ERG30, a VAP-33-related protein, functions in protein transport mediated by COPI vesicles.  Journal of Cell Biology. 1999 Jul , 146 (2):301-311.
  101. Legesse-Miller A., Sagiv Y., Porat A. & Elazar Z. (1998). Isolation and characterization of a novel low molecular weight protein involved in intra-Golgi traffic.  Journal of Biological Chemistry. 1998 Jan , 273 (5):3105-3109.
  102. Mayer T., Touchot N. & Elazar Z. (1996). Transport between cis and medial Golgi Cisternae Requires the Function of the Ras-related Protein Rab6.  Journal of Biological Chemistry. 1996 Jul , 271 (27):16097-16103.
  103. FISHBURN C., Elazar Z. & Fuchs S. (1995). Differential Glycosylation and Intracellular Trafficking for the Long and Short Isoforms of the D2 Dopamine Receptor.  Journal of Biological Chemistry. 1995 Dec , 270 (50):29819-29824.
  104. Elazar Z., Mayer T. & Rothman J. E. (1994). Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks.  The journal of Biological chemistry. 1994 Jan , 269 (2):794-797.
  105. Elazar Z., Orci L., Ostermann J., Amherdt M., Tanigawa G. & Rothman J. E. (1994). ADP-ribosylation factor and coatomer couple fusion to vesicle budding.  The Journal of Cell Biology. 1994 Feb , 124 (4):415-424.
  106. Ostermann J., Orci L., Tani K., Amherdt M., Ravazzola M., Elazar Z. & Rothman J. E. (1993). Stepwise assembly of functionally active transport vesicles.  Cell. 1993 Dec , 75 (5):1015-1025.
  107. Elazar Z. & Fuchs S. (1991). Phosphorylation by Cyclic AMPDependent Protein Kinase Modulates Agonist Binding to the D2 Dopamine Receptor.  Journal of Neurochemistry. 1991 Jan , 56 (1):75-80.
  108. Elazar Z. & Fuchs S. (1991). Vanadate inhibits agonist binding to D2 dopamine receptor.  Journal of Molecular Neuroscience. 1991 Mar , 3 (1):1-6.
  109. Elazar Z., SIEGEL G. & Fuchs S. (1989). Association of two pertussis toxinsensitive Gproteins with the D2dopamine receptor from bovine striatum.  EMBO Journal. 1989 Aug , 8 (8):2353-2357.
  110. Elazar Z., KANETY H., SCHREIBER M. & Fuchs S. (1988). Anti-idiotypes against a monoclonal anti-haloperidol antibody bind to dopamine receptor.  Life Sciences. 1988, 42 (20):1987-1993.
  111. KANETY H., SCHREIBER M., Elazar Z. & Fuchs S. (1988). Antibodies against haloperidol specific to the butyrophenone moiety.  Journal of Neuroimmunology. 1988 Apr , 18 (1):25-36.
  112. Elazar Z., KANETY H., DAVID C. & Fuchs S. (1988). Purification of the D-2 dopamine receptor from bovine striatum.  Biochemical and Biophysical Research Communications. 1988 Oct , 156 (1):602-609.
Contact: Zvulun Elazar | Tel: +972-8-934-3682 | Fax: +972-8-934-2592