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2024
The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
Read more about![The CD8<sup>+</sup> T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/default_images/pub_8.jpg?itok=0IYAnLJP)
Modeling T cell temporal response to cancer immunotherapy rationalizes development of combinatorial treatment protocols
Read more about![Modeling T cell temporal response to cancer immunotherapy rationalizes development of combinatorial treatment protocols](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/modeling_t_cell_temporal_response_to_cancer_immunotherapy_rationalizes_development_of_combinatorial_treatment_protocols.jpg?itok=ADxI-Ez3)
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma
Read more about![Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/time-resolved_single-cell_transcriptomics_defines_immune_trajectories_in_glioblastoma_0.jpg?itok=LDxrqdng)
Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz
Read more about![Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/regulation_of_lymphoid-myeloid_lineage_bias_through_regnase-1-3-mediated_control_of_nfkbiz_1.jpg?itok=siBJILhe)
Bispecific dendritic-T cell engager potentiates anti-tumor immunity
Read more about![Bispecific dendritic-T cell engager potentiates anti-tumor immunity](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/bispecific_dendritic-t_cell_engager_potentiates_anti-tumor_immunity_0.jpg?itok=xOi-ZGc3)
2023
Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
Read more about![Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/spatial_and_temporal_mapping_of_breast_cancer_lung_metastases_identify_trem2_macrophages_as_regulators_of_the_metastatic_boundary.jpg?itok=M9PoC5SJ)
Neural plate progenitors give rise to both anterior and posterior pituitary cells
Read more about![Neural plate progenitors give rise to both anterior and posterior pituitary cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/neural_plate_progenitors_give_rise_to_both_anterior_and_posterior_pituitary_cells_0.jpg?itok=3CAJgShh)
Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis
Read more about![Cholesterol 24-hydroxylase at the choroid plexus contributes to brain immune homeostasis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/cholesterol_24-hydroxylase_at_the_choroid_plexus_contributes_to_brain_immune_homeostasis_0.jpg?itok=yO0as_n9)
An immune cell atlas reveals the dynamics of human macrophage specification during prenatal development
Read more about![An immune cell atlas reveals the dynamics of human macrophage specification during prenatal development](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/an_immune_cell_atlas_reveals_the_dynamics_of_human_macrophage_specification_during_prenatal_development.jpg?itok=Bj3wOzML)
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsufficiency
Read more about![Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsufficiency](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/cellular_and_metabolic_characteristics_of_pre-leukemic_hematopoietic_progenitors_with_gata2_haploinsuficiency.jpg?itok=E8MGAus7)
Single-cell biology: what does the future hold?
Read more about![Single-cell biology: what does the future hold?](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/blank_1.jpg?itok=NzoFqCn4)
Editorial: Microglia in neuroinflammation
Read more about![Editorial: Microglia in neuroinflammation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/blank_0.jpg?itok=GwdZIyZ4)
In Synergy: Optimizing CAR T Development and Personalizing Patient Care Using Single-Cell Technologies
Read more about![In Synergy: Optimizing CAR T Development and Personalizing Patient Care Using Single-Cell Technologies](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/in_synergy-_optimizing_car_t_development_and_personalizing_patient_care_using_single-cell_technologies_1.jpg?itok=4AiL_x7b)
Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma
Read more about![Targeted delivery of tumor necrosis factor in combination with CCNU induces a T cell-dependent regression of glioblastoma](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/targeted_delivery_of_tumor_necrosis_factor_in_combination_with_ccnu_induces_a_t_cell-dependent_regression_of_glioblastoma_0.jpg?itok=_E0JxlWB)
Immunometabolism at the crossroads of obesity and cancer—a Keystone Symposia report
Read more about![Immunometabolism at the crossroads of obesity and cancer—a Keystone Symposia report](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/blank.jpg?itok=m4q5wssb)
The transcriptional and regulatory identity of erythropoietin producing cells
Read more about![The transcriptional and regulatory identity of erythropoietin producing cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/the_transcriptional_and_regulatory_identity_of_erythropoietin_producing_cells_2_5.jpg?itok=IG2j0DEe)
A single-cell census of mouse limb development identifies complex spatiotemporal dynamics of skeleton formation
Read more about![A single-cell census of mouse limb development identifies complex spatiotemporal dynamics of skeleton formation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/a_single-cell_census_of_mouse_limb_development_identifies_complex_spatiotemporal_dynamics_of_skeleton_formation_1.jpg?itok=4-rn3Stf)
Author Correction: A shared disease-associated oligodendrocyte signature among multiple CNS pathologies (Nature Neuroscience, (2022), 25, 7, (876-886), 10.1038/s41593-022-01104-7)
Read more about![Author Correction: A shared disease-associated oligodendrocyte signature among multiple CNS pathologies (Nature Neuroscience, (2022), 25, 7, (876-886), 10.1038/s41593-022-01104-7)](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/default_images/pub_8.jpg?itok=0IYAnLJP)
Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy
Read more about![Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/fc_glycoengineering_of_a_pd-l1_antibody_harnesses_fcg_receptors_for_increased_antitumor_efficacy.jpg?itok=mX1ax7u6)
Cerebrospinal fluid proteomics indicates immune dysregulation and neuronal dysfunction in antibody associated autoimmune encephalitis
Read more about![Cerebrospinal fluid proteomics indicates immune dysregulation and neuronal dysfunction in antibody associated autoimmune encephalitis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/cerebrospinal_fluid_proteomics_indicates_immune_dysregulation_and_neuronal_dysfunction_in_antibody_associated_autoimmune_encephalitis.jpg?itok=i3B1Xnzy)
Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development
Read more about![Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/neighbor-specific_gene_expression_revealed_from_physically_interacting_cells_during_mouse_embryonic_development.jpg?itok=fOJT9LWv)
Erratum: C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells (Cell Stem Cell (2020) 26(5) (657–674.e8), (S1934590920300175), (10.1016/j.stem.2020.01.017))
Read more about![Erratum: C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells (Cell Stem Cell (2020) 26(5) (657–674.e8), (S1934590920300175), (10.1016/j.stem.2020.01.017))](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/c_ebpv-dependent_epigenetic_memory_induces_trained_immunity_in_hematopoietic_stem_cells_0.jpg?itok=_zK2nSGg)
2022
Distinct gene programs underpinning disease tolerance and resistance in influenza virus infection
Read more about![Distinct gene programs underpinning disease tolerance and resistance in influenza virus infection](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/distinct_gene_programs_underpinning_disease_tolerance_and_resistance_in_influenza_virus_infection_1.jpg?itok=EbL64fjL)
A spatiotemporally resolved single-cell atlas of the Plasmodium liver stage
Read more about![A spatiotemporally resolved single-cell atlas of the Plasmodium liver stage](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/a_spatiotemporally_resolved_single-cell_atlas_of_the_plasmodium_liver_stage.jpg?itok=dPpBPzGo)
Microglia states and nomenclature: A field at its crossroads
Read more about![Microglia states and nomenclature: A field at its crossroads](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/microglia_states_and_nomenclature-_a_field_at_its_crossroads.jpg?itok=DvnptM36)
Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling
Read more about![Anti-CTLA-4 antibodies drive myeloid activation and reprogram the tumor microenvironment through FcγR engagement and type I interferon signaling](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/anti-ctla-4_antibodies_drive_myeloid_activation_and_reprogram_the_tumor_microenvironment_through_fcgr_engagement_and_type_i_interferon_signaling_0.jpg?itok=8ZlGtl2i)
The industrial genomic revolution: A new era in neuroimmunology
Read more about![The industrial genomic revolution: A new era in neuroimmunology](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/the_industrial_genomic_revolution-_a_new_era_in_neuroimmunology.jpg?itok=prrIUzgq)
Spatiotemporal Omics-Refining the landscape of precision medicine
Read more about![Spatiotemporal Omics-Refining the landscape of precision medicine](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/spatiotemporal_omics-refining_the_landscape_of_precision_medicine_0.jpg?itok=xIqe4jlR)
Rejuvenation strategies share gene expression programs of reduced inflammation and downstream restored fatty acid metabolism
Read more about![Rejuvenation strategies share gene expression programs of reduced inflammation and downstream restored fatty acid metabolism](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/rejuvenation_strategies_share_gene_expression_programs_of_reduced_inflammation_and_downstream_restored_fatty_acid_metabolism_0.jpg?itok=kApPdwKU)
Time-resolved single-cell RNA-seq using metabolic RNA labelling
Read more about![Time-resolved single-cell RNA-seq using metabolic RNA labelling](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/time-resolved_single-cell_rna-seq_using_metabolic_rna_labelling_0.jpg?itok=y9h-yGqr)
DestVI identifies continuums of cell types in spatial transcriptomics data
Read more about![DestVI identifies continuums of cell types in spatial transcriptomics data](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/3_0.png?itok=QqLusYC9)
Human microglia development in the embryonic brain
Read more about![Human microglia development in the embryonic brain](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/human_microglia_development_in_the_embryonic_brain.jpg?itok=XOJIoqP8)
Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration
Read more about![Dual ontogeny of disease-associated microglia and disease inflammatory macrophages in aging and neurodegeneration](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/dual_ontogeny_of_disease-associated_microglia_and_disease_inflammatory_macrophages_in_aging_and_neurodegeneration_0.jpg?itok=eriKd7UH)
A shared disease-associated oligodendrocyte signature among multiple CNS pathologies
Read more about![A shared disease-associated oligodendrocyte signature among multiple CNS pathologies](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/a_shared_disease-associated_oligodendrocyte_signature_among_multiple_cns_pathologies.jpg?itok=DbZ8x77x)
Physically interacting beta-delta pairs in the regenerating pancreas revealed by single-cell sequencing
Read more about![Physically interacting beta-delta pairs in the regenerating pancreas revealed by single-cell sequencing](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/1-s2.0-s2212877822000369-gr5.jpg?itok=hxf8NWHe)
Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics
Read more about![Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/identification_of_the_central_intermediate_in_the_extra-embryonic_to_embryonic_endoderm_transition_through_single-cell_transcriptomics.gif?itok=qNr5hxRd)
Brain metastases: Not all tumors are created equal
Read more about![Brain metastases: Not all tumors are created equal](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/brain_metastases-_not_all_tumors_are_created_equal_3.gif?itok=A6DkgHJZ)
LGR5 expressing skin fibroblasts define a major cellular hub perturbed in scleroderma
Read more about![LGR5 expressing skin fibroblasts define a major cellular hub perturbed in scleroderma](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/lgr5_expressing_skin_fibroblasts_define_a_major_cellular_hub_perturbed_in_scleroderma_2.gif?itok=p9TH2X3c)
Single-cell immunology: Past, present, and future
Read more about![Single-cell immunology: Past, present, and future](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/fnufrjaxwaa_lub.jpeg?itok=kzaYlUG7)
The interaction of CD4+ helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response
Read more about![The interaction of CD4<sup>+</sup> helper T cells with dendritic cells shapes the tumor microenvironment and immune checkpoint blockade response](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/picture_tweet2.png?itok=OXRKmNmt)
Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting
Read more about![Bispecific antibodies increase the therapeutic window of CD40 agonists through selective dendritic cell targeting](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/bispecific_antibodies_increase_the_therapeutic_window_of_cd40_agonists_through_selective_dendritic_cell_targeting-_pic.gif?itok=eFK2431C)
Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis
Read more about![Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/fatal_cytokine_release_syndrome_by_an_aberrant_flip-stat3_axis.jpg?itok=fT78e7qh)
Publisher Correction: XCR1 + type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis (Nature Medicine, (2021), 27, 6, (1043-1054), 10.1038/s41591-021-01344-3)
Read more about![Publisher Correction: XCR1
<sup>+</sup> type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis (Nature Medicine, (2021), 27, 6, (1043-1054), 10.1038/s41591-021-01344-3)](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/xcr1_type_1_conventional_dendritic_cells_drive_liver_pathology_in_non-alcoholic_steatohepatitis.jpg?itok=6t1sHN9A)
Alzheimer’s disease modification mediated by bone marrow-derived macrophages via a TREM2-independent pathway in mouse model of amyloidosis
Read more about![Alzheimer’s disease modification mediated by bone marrow-derived macrophages via a TREM2-independent pathway in mouse model of amyloidosis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/2.png?itok=aFW5CRrO)
Early antitumor activity of oral Langerhans cells is compromised by a carcinogen
Read more about![Early antitumor activity of oral Langerhans cells is compromised by a carcinogen](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/f1.large_.jpg?itok=LZAa2ERV)
2021
Clump sequencing exposes the spatial expression programs of intestinal secretory cells
Read more about![Clump sequencing exposes the spatial expression programs of intestinal secretory cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/41467_2021_23245_fig1_html_copy.jpg?itok=jEgL15Gp)
Dichotomous metabolic networks govern human ILC2 proliferation and function
Read more about![Dichotomous metabolic networks govern human ILC2 proliferation and function](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/41590_2021_1043_fig1_html.png?itok=H3rL2lhk)
Single-cell analysis of regions of interest (SCARI) using a photosensitive tag
Read more about![Single-cell analysis of regions of interest (SCARI) using a photosensitive tag](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/41589_2021_839_figa_html.png?itok=DPhUtRpt)
Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development
Read more about![Tumor cells in light-chain amyloidosis and myeloma show distinct transcriptional rewiring of normal plasma cell development](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/tumor_cells_in_light-chain_amyloidosis_and_myeloma_show_distinct_transcriptional_rewiring_of_normal_plasma_cell_development_0.jpg?itok=2qASLSY4)
Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation
Read more about![Multi-tissue single-cell analysis deconstructs the complex programs of mouse natural killer and type 1 innate lymphoid cells in tissues and circulation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/1-s2.0-s1074761321001369-fx1.jpg?itok=xQJtiiW2)
XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
Read more about![XCR1<sup>+</sup> type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/15.png?itok=3zV9QH84)
Heads or tails: histone tail clipping regulates macrophage activity
Read more about![Heads or tails: histone tail clipping regulates macrophage activity](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/41590_2021_941_fig1_html_copy.jpg?itok=-E4Nv7eg)
A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion
Read more about![A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/41467_2021_23295_fig3_html.png-2.png?itok=lJp3eASj)
NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Read more about![NASH limits anti-tumour surveillance in immunotherapy-treated HCC](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/screen_shot_2021-04-18_at_16.48.38.png?itok=3aLCiiTE)
Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing
Read more about![Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/3.png?itok=B_ZgVOvL)
Deciphering the state of immune silence in fatal COVID-19 patients
Read more about![Deciphering the state of immune silence in fatal COVID-19 patients](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/image_1.jpeg?itok=eiIXTjhc)
Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies
Read more about![Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/meningezz.png?itok=420bh7Xj)
NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis
Read more about![NF-κB activity during pancreas development regulates adult β-cell mass by modulating neonatal β-cell proliferation and apoptosis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/capture_2.png?itok=KDrQrQyt)
Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors
Read more about![Bi-fated tendon-to-bone attachment cells are regulated by shared enhancers and KLF transcription factors](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/huhuhu.png?itok=bdPYgFOB)
2020
A single cell atlas of the human liver tumor microenvironment
Read more about![A single cell atlas of the human liver tumor microenvironment](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/liver.png?itok=fzzXNWCx)
LifeTime and improving European healthcare through cell-based interceptive medicine
Read more about![LifeTime and improving European healthcare through cell-based interceptive medicine](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/ff.png?itok=YjxZhi96)
Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19
Read more about![Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/ddddd.png?itok=u0phvlR0)
Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer
Read more about![Coupled scRNA-Seq and Intracellular Protein Activity Reveal an Immunosuppressive Role of TREM2 in Cancer](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/katza.png?itok=A__RL9Dj)
Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4(+) and PDPN+ CAFs to clinical outcome
Read more about![Cancer-associated fibroblast compositions change with breast cancer progression linking the ratio of S100A4(+) and PDPN+ CAFs to clinical outcome](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/43018_2020_82_fig1_html.png?itok=QbBXPlFb)
Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
Read more about![Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/jokojoko.png?itok=TFsM5S2p)
Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19
Read more about![Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/dfdfdf.png?itok=lUf7ewGy)
The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway
Read more about![The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/capture.png?itok=XALhg82s)
Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients
Read more about![Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/capture_0.png?itok=9PTjNr2n)
Dissecting cellular crosstalk by sequencing physically interacting cells
Read more about![Dissecting cellular crosstalk by sequencing physically interacting cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/pic.jpg?itok=kWwQ24rS)
Cxcl10(+) monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation
Read more about![Cxcl10(+) monocytes define a pathogenic subset in the central nervous system during autoimmune neuroinflammation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/mildner.png?itok=Pgfpob-Q)
C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells
Read more about![C/EBPβ-Dependent Epigenetic Memory Induces Trained Immunity in Hematopoietic Stem Cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/hh.png?itok=ZYexKgTt)
Lgr5+telocytes are a signaling source at the intestinal villus tip
Read more about![Lgr5+telocytes are a signaling source at the intestinal villus tip](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/shoshkes.png?itok=CYyej4Ac)
Bystander IFN-gamma activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment
Read more about![Bystander IFN-gamma activity promotes widespread and sustained cytokine signaling altering the tumor microenvironment](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/kokoko.png?itok=FL3GlWYZ)
Single-cell genomic approaches for developing the next generation of immunotherapies
Read more about![Single-cell genomic approaches for developing the next generation of immunotherapies](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/yofe.jpg?itok=4PVgs5J5)
Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4(+) T cells
Read more about![Spatiotemporal regulation of type I interferon expression determines the antiviral polarization of CD4(+) T cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/rrrcapturerrr.jpg?itok=mUMfJV2K)
2019
Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program
Read more about![Cross-Species Single-Cell Analysis Reveals Divergence of the Primate Microglia Program](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/mic_0.png?itok=Q3rZPVYL)
ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma
Read more about![ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/koko.jpg?itok=JVrD9DoG)
Plasmacytoid dendritic cells develop from Ly6D(+) lymphoid progenitors distinct from the myeloid lineage
Read more about![Plasmacytoid dendritic cells develop from Ly6D(+) lymphoid progenitors distinct from the myeloid lineage](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/kokoko.jpg?itok=fd8ofNzH)
A niche-dependent myeloid transcriptome signature defines dormant myeloma cells
Read more about![A niche-dependent myeloid transcriptome signature defines dormant myeloma cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/kosc.jpg?itok=JbSaOLPm)
Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations
Read more about![Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/capture_0.jpg?itok=S9oxW1A8)
MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing
Read more about![MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/lolo.jpg?itok=wB6FHml8)
Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress
Read more about![Corticosteroid signaling at the brain-immune interface impedes coping with severe psychological stress](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/capture.jpg?itok=ej-wOBQ5)
Cell composition analysis of bulk genomics using single-cell data
Read more about![Cell composition analysis of bulk genomics using single-cell data](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/konoko_0.jpg?itok=tZfyg6TM)
DC Respond to Cognate T Cell Interaction in the Antigen-Challenged Lymph Node
Read more about![DC Respond to Cognate T Cell Interaction in the Antigen-Challenged Lymph Node](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/curato.jpg?itok=fGam2GYD)
Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma
Read more about![Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/2d.png?itok=2VmIvrMG)
Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules
Read more about![Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/xxx.jpg?itok=TyThS3jb)
Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity
Read more about![Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/picture1_1.jpg?itok=UivCjVWs)
PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model
Read more about![PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/998_0.png?itok=wMvu8KU3)
2018
Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma
Read more about![Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/993.jpg?itok=sJxWGRcE)
Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting
Read more about![Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/991x.jpg?itok=vmIZUUGs)
From the Human Cell Atlas to dynamic immune maps in human disease
Read more about![From the Human Cell Atlas to dynamic immune maps in human disease](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/993.png?itok=Ii4aMX55)
Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling
Read more about![Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/997.png?itok=09cYs9So)
Early metazoan cell type diversity and the evolution of multicellular gene regulation
Read more about![Early metazoan cell type diversity and the evolution of multicellular gene regulation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/994xxx.jpg?itok=W3-kSvyO)
Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis
Read more about![Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/987.png?itok=j1wiU8Ur)
The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation
Read more about![The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/983.png?itok=aVoLIuiL)
Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells
Read more about![Single-cell mapping of the thymic stroma identifies IL-25-producing tuft epithelial cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/il25.jpg?itok=fpJR93pe)
Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment
Read more about![Differences in Cell Cycle Status Underlie Transcriptional Heterogeneity in the HSC Compartment](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/hsc.jpg?itok=w5UUuwTe)
Dissection of Influenza Infection In Vivo by Single-Cell RNA Sequencing
Read more about![Dissection of Influenza Infection In Vivo by Single-Cell RNA Sequencing](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/flu_papaer.jpg?itok=msqkEaxX)
Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies
Read more about![Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/uterine_nk.jpg?itok=ak-LCIyY)
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
Read more about![Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/996.jpg?itok=RsgSHxb3)
Microglial immune checkpoint mechanisms
Read more about![Microglial immune checkpoint mechanisms](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/990.jpg?itok=hq6oqNxn)
Salient experiences are represented by unique transcriptional signatures in the mouse brain
Read more about![Salient experiences are represented by unique transcriptional signatures in the mouse brain](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/cocaine.jpg?itok=GsYptBhW)
A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies
Read more about![A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/kok_0.jpg?itok=no6H7YbA)
Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner
Read more about![Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/picture1.jpg?itok=Uecfp1Wq)
Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries
Read more about![Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/985.jpg?itok=t5CLIoST)
2017
Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner
Read more about![Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/973x.png?itok=vQ8azjQv)
Science Forum: The Human Cell Atlas
Read more about![Science Forum: The Human Cell Atlas](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/science_forum-_the_human_cell_atlas.jpg?itok=7_yRVKoc)
Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq
Read more about![Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/969.jpg?itok=WSw2Ayox)
Immunology, one cell at a time
Read more about![Immunology, one cell at a time](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/13735f185_resize.jpg?itok=NXDvT8Jn)
MicroRNA-142 controls thymocyte proliferation
Read more about![MicroRNA-142 controls thymocyte proliferation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/mir142.jpg?itok=BaNXOYkg)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Read more about![A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/975_0.jpg?itok=QLmpqBPu)
Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain
Read more about![Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/kikik.jpg?itok=-cTxVTWy)
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses
Read more about![Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/hohohoh.jpg?itok=dO6_zMPG)
Genomic Characterization of Murine Monocytes Reveals C/EBP beta Transcription Factor Dependence of Ly6C(-) Cells
Read more about![Genomic Characterization of Murine Monocytes Reveals C/EBP beta Transcription Factor Dependence of Ly6C(-) Cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/jijijij.jpg?itok=XPBaoPI5)
Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation
Read more about![Autonomous TNF is critical for in vivo monocyte survival in steady state and inflammation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/jojo.jpg?itok=8G8XI9qh)
Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression
Read more about![Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/kpkpkp.jpg?itok=z_lJHFoe)
Single-cell transcriptome conservation in cryopreserved cells and tissues
Read more about![Single-cell transcriptome conservation in cryopreserved cells and tissues](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/hyhyhy.jpg?itok=GslH6kmF)
Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation
Read more about![Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/juju.jpg?itok=M_iofKmB)
Transcriptional programs that control expression of the autoimmune regulator gene Aire
Read more about![Transcriptional programs that control expression of the autoimmune regulator gene Aire](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/komo.jpg?itok=sWAIKqXp)
CD74 is a novel transcription regulator
Read more about![CD74 is a novel transcription regulator](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/cd47.jpg?itok=RHSsDOC_)
2016
Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq
Read more about![Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/crisprseq.jpg?itok=6Wa570bt)
Extracellular Matrix Proteolysis by MT1-MMP Contributes to Influenza-Related Tissue Damage and Mortality
Read more about![Extracellular Matrix Proteolysis by MT1-MMP Contributes to Influenza-Related Tissue Damage and Mortality](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/nini.jpg?itok=7U2YAa22)
Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution
Read more about![Co-ChIP enables genome-wide mapping of histone mark co-occurrence at single-molecule resolution](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/cochip.jpg?itok=Jc7cTboD)
Distinct biological events generated by ECM proteolysis by two homologous collagenases
Read more about![Distinct biological events generated by ECM proteolysis by two homologous collagenases](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/962.gif?itok=D322h6NK)
Microglia development follows a stepwise program to regulate brain homeostasis
Read more about![Microglia development follows a stepwise program to regulate brain homeostasis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/958.jpg?itok=DAXVklZ1)
M-sec regulates polarized secretion of inflammatory endothelial chemokines and facilitates CCL2-mediated lymphocyte transendothelial migration
Read more about![M-sec regulates polarized secretion of inflammatory endothelial chemokines and facilitates CCL2-mediated lymphocyte transendothelial migration](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/957.png?itok=L7rcv806)
Voices Of Biotech
Read more about![Voices Of Biotech](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/952.png?itok=h9yLs2Yh)
Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing
Read more about![Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/955.jpg?itok=kByZ0Z1D)
PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease
Read more about![PD-1 immune checkpoint blockade reduces pathology and improves memory in mouse models of Alzheimer's disease](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/pd1.jpg?itok=2aDmSmT7)
The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis
Read more about![The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/954.jpg?itok=SXm4V1ae)
2015
Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors
Read more about![Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/938_0.jpg?itok=XXWjq3qY)
From mass cytometry to cancer prognosis
Read more about![From mass cytometry to cancer prognosis](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/945.jpg?itok=WsChTOnJ)
Making the case for chromatin profiling: A new tool to investigate the immune-regulatory landscape
Read more about![Making the case for chromatin profiling: A new tool to investigate the immune-regulatory landscape](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/941.jpg?itok=V35Iv65k)
Distinct Murine Mucosal Langerhans Cell Subsets Develop from Pre-dendritic Cells and Monocytes
Read more about![Distinct Murine Mucosal Langerhans Cell Subsets Develop from Pre-dendritic Cells and Monocytes](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/947.jpg?itok=JqGRU-xs)
DCs are ready to commit
Read more about![DCs are ready to commit](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/951.jpg?itok=8obryUbn)
Derivation of novel human ground state naive pluripotent stem cells (vol 504, pg 282, 2013): Derivation of novel human ground state naive pluripotent stem cells
Read more about![Derivation of novel human ground state naive pluripotent stem cells (vol 504, pg 282, 2013): Derivation of novel human ground state naive pluripotent stem cells](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/920xx_1.jpg?itok=HgvsglyQ)
Deterministic direct reprogramming of somatic cells to pluripotency (vol 502, pg 65, 2013): Deterministic direct reprogramming of somatic cells to pluripotency (Nature (2013) 502 (65-70) DOI: 10.1038/nature12587)
Read more about![Deterministic direct reprogramming of somatic cells to pluripotency (vol 502, pg 65, 2013): Deterministic direct reprogramming of somatic cells to pluripotency (Nature (2013) 502 (65-70) DOI: 10.1038/nature12587)](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/919x.jpg?itok=8lYUokkK)
Simultaneous measurement of genome-wide transcription elongation speeds and rates of RNA polymerase II transition into active elongation with 4sUDRB-seq
Read more about![Simultaneous measurement of genome-wide transcription elongation speeds and rates of RNA polymerase II transition into active elongation with 4sUDRB-seq](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/939.jpg?itok=UqFsu9qn)
High-resolution chromatin dynamics during a yeast stress response
Read more about![High-resolution chromatin dynamics during a yeast stress response](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/944.jpg?itok=6b1VeIgu)
Transcription factor binding dynamics during human ES cell differentiation
Read more about![Transcription factor binding dynamics during human ES cell differentiation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/937.jpg?itok=I2tEmr1W)
m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation
Read more about![m<sup>6</sup>A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/942.jpg?itok=CHRrB_2C)
Each cell counts: Hematopoiesis and immunity research in the era of single cell genomics
Read more about![Each cell counts: Hematopoiesis and immunity research in the era of single cell genomics](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/946.jpg?itok=-lgMOxPL)
2014
A Negative Feedback Loop of Transcription Factors Specifies Alternative Dendritic Cell Chromatin States
Read more about![A Negative Feedback Loop of Transcription Factors Specifies Alternative Dendritic Cell Chromatin States](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/932.jpg?itok=OFv3ryHl)
Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7-dependent manner
Read more about![Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7-dependent manner](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/930.png?itok=fvv13y6k)
Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment
Read more about![Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/922.jpg?itok=oombem4U)
High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies
Read more about![High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/928.png?itok=WGlrTEDi)
Plasticity in the transcriptional and epigenetic circuits regulating dendritic cell lineage specification and function
Read more about![Plasticity in the transcriptional and epigenetic circuits regulating dendritic cell lineage specification and function](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/926.png?itok=qmBRTLyk)
The central nervous system microenvironment imprints microglial inability to switch from pro- to anti-inflammatory phenotype
Read more about![The central nervous system microenvironment imprints microglial inability to switch from pro- to anti-inflammatory phenotype](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/924.png?itok=7fPg6YKg)
Aging-induced type I interferon response at the choroid plexus negatively affects brain function
Read more about![Aging-induced type I interferon response at the choroid plexus negatively affects brain function](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/plplpl.jpg?itok=pJQSyCr1)
The role of chromatin dynamics in immune cell development
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Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators
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Chromatin state dynamics during blood formation
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Digital cell quantification identifies global immune cell dynamics during influenza infection
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Sequential feedback induction stabilizes the phosphate starvation response in budding yeast
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Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types
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4sUDRB-seq: measuring genomewide transcriptional elongation rates and initiation frequencies within cells
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2013
Semiconductor-based DNA sequencing of histone modification states
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Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli
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Mononuclear phagocyte miRNome analysis identifies miR-142 as critical regulator of murine dendritic cell homeostasis
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High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states
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Deterministic direct reprogramming of somatic cells to pluripotency
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Derivation of novel human ground state naive pluripotent stem cells
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2012
Nanowire-mediated delivery enables functional interrogation of primary immune cells: Application to the analysis of chronic lymphocytic leukemia
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A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals
Read more about![A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/a_high-throughput_chromatin_immunoprecipitation_approach_reveals_principles_of_dynamic_gene_regulation_in_mammals.jpg?itok=inJZNYaf)
The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming
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Expression Noise and Acetylation Profiles Distinguish HDAC Functions
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EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF
Read more about![EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF](https://www.weizmann.ac.il/immunology/AmitLab/sites/immunology.AmitLab/files/styles/570x295/public/915.png?itok=OUalq7u_)
M(odu)LLating the Innate Response
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2011
Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells
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Strategies to discover regulatory circuits of the mammalian immune system
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Systematic discovery of TLR signaling components delineates viral-sensing circuits
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2010
EGF decreases the abundance of MicroRNAs that restrain oncogenic transcription factors
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2007
Systems approach to growth factor signaling and to therapeutic intervention
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A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration
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Regulation of MAPKs by growth factors and receptor tyrosine kinases
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A module of negative feedback regulators defines growth factor signaling
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Evolvable signaling networks of receptor tyrosine kinases: Relevance of robustness to malignancy and to cancer therapy
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2005
Suppressors of cytokine signaling 4 and 5 regulate epidermal growth factor receptor signaling
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2004
LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation
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Tal, a Tsg101-specific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus budding
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