Genome databases, Origin of life

Decipher expression of molecular pathways and their function in cells, disease models and samples from patients.

Why do some people succumb to infection - while others don't?

Personalized medicine using machine learning applied to genomic and clinical data

Human evolution and disease

The interplay between viruses and their hosts

Design principle of Biological circuits. Ageing and Age-related disease

We study how antibodies are generated in response to invading pathogens in mouse models, infected subjects and cancer patients. We use this information to produce novel antibodies for immunotherapy.

Developing experimental and computational approaches for multiplexed imaging of clinical specimens to uncover tumor-immune interactions

Spatial transcriptomics of mammalian tissues

Molecular pathogenesis of neurodegenerative diseases

We study interactions between peripheral circadian clocks and exercise physiology, hypoxia signaling and metabolic pathways

Understanding epithelial, stem and immune cell interactions in the gut

We study the structure, function and evolution of systems that regulate gene expression, with emphasis on translation

Combining data analysis and experimental methods for understanding tissue function from single cells