January 07, 1995 - January 07, 2028

  • Date:06MondayJanuary 2025

    From mechanisms to evolution: Understanding genetic variation with long-read sequencing

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    Time
    11:30 - 12:30
    Title
    The Department of Molecular Cell Biology and the Department of Molecular Genetics Guest Seminar
    Location
    Wolfson
    Auditorium
    LecturerDr. Regev Schweiger
    Organizer
    Department of Molecular Cell Biology
    Contact
    AbstractShow full text abstract about <p>Patterns of genetic variation we observe today hold...»
    <p>Patterns of genetic variation we observe today hold echoes of the ancestral events that shaped them. Population genetics - the study of genetic variation - offers a window into this past, providing insights across evolutionary biology, history, and human health. Advances in long-read sequencing technology, combined with the rapid decrease in sequencing costs, open new avenues for studying genetic variation. In my talk, I will focus on two such examples: First, how long-read sperm sequencing is uncovering new insights into meiotic recombination, with emphasis on non-crossover recombination. Second, algorithms based on coalescent theory for recovering evolutionary histories, with applications ranging from the deep evolutionary history of humans to detecting natural selection on genetic variants.</p>
    Lecture