Publications
Giannoulis A., Feintuch A., Barak Y., Mazal H., Albeck S., Unger T., Yang F., Su X. & Goldfarb D.
(2020).
Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques.
Proceedings of the National Academy of Sciences of the United States of America.
117:(1)395-404.
Prabahar V., Afriat-Jurnou L., Paluy I., Peleg Y. & Noy D.
(2020).
New homologues of Brassicaceae water-soluble chlorophyll proteins shed light on chlorophyll binding, spectral tuning, and molecular evolution.
FEBS Journal.
287:(5)991-1004.
Suzumoto Y., Dym O., Roviello G. N., Worek F., Sussman J. L. & Manco G.
(2020).
Structural and functional characterization of new ssopox variant points to the dimer interface as a driver for the increase in promiscuous paraoxonase activity.
International Journal of Molecular Sciences.
21:(5)
Rosenthal M., Metzl-Raz E., Buergi J., Yifrach E., Drwesh L., Fadel A., Peleg Y., Rapaport D., Wilmanns M., Barkai N., Schuldiner M. & Zalckvar E.
(2020).
Uncovering targeting priority to yeast peroxisomes using an in-cell competition assay.
Proceedings of the National Academy of Sciences of the United States of America.
117:(35)21432-21440.
Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Ben Nissan G., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J.
(2019).
Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.
PLoS Computational Biology.
15:(8)
Dalaloyan A., Martorana A., Barak Y., Gataulin D., Reuveny E., Howe A., Elbaum M., Albeck S., Unger T., Frydman V., Abdelkader E. H., Otting G. & Goldfarb D.
(2019).
Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements.
ChemPhysChem.
20:(14)1860-1868.
Karbat I., Altman-Gueta H., Fine S., Szanto T., Hamer-Rogotner S., Dym O., Frolow F., Gordon D., Panyi G., Gurevitz M. & Reuveny E.
(2019).
Pore-modulating toxins exploit inherent slow inactivation to block K+ channels.
Proceedings of the National Academy of Sciences of the United States of America.
116:(37)18700-18709.
Novichkova D. A., Lushchekina S., Dym O., Masson P., Silman I. & Sussman J. L.
(2019).
The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability.
Chemico-Biological Interactions.
309.
Zahradnik J., Kolarova L., Peleg Y., Kolenko P., Svidenska S., Charnavets T., Unger T., Sussman J. L. & Schneider B.
(2019).
Flexible regions govern promiscuous binding of IL-24 to receptors IL-20R1 and IL-22R1.
FEBS Journal.
286:(19)3858-3873.
Arafeh R., Di Pizio A., Elkahloun A. G., Dym O., Niv M. Y. & Samuels Y.
(2019).
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma.
Oncogene.
38:(13)2432-2434.
Kantaev R., Riven I., Goldenzweig A., Barak Y., Dym O., Peleg Y., Albeck S., Fleishman S. J. & Haran G.
(2018).
Manipulating the Folding Landscape of a Multi-Domain Protein.
Journal of Physical Chemistry B.
122:(49)11030-11038.
Netzer R., Listov D., Lipsh R., Dym O., Albeck S., Knop O., Kleanthous C. & Fleishman S. J.
(2018).
Ultrahigh specificity in a network of computationally designed protein-interaction pairs.
Nature Communications.
9:(1)
Elad N., Baron S., Peleg Y., Albeck S., Grunwald J., Raviv G., Shakked Z., Zimhony O. & Diskin R.
(2018).
Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution.
Nature Communications.
9:(1)
Karniel A., Mrusek D., Steinchen W., Dym O., Bange G. & Bibi E.
(2018).
Co-translational folding intermediate dictates membrane targeting of the signal recognition particle-receptor.
Journal of Molecular Biology.
430:(11)1607-1620.
Bandyopadhyay B. & Peleg Y.
(2018).
Facilitating circular permutation using Restriction Free (RF) cloning.
Protein Engineering Design & Selection.
31:(3)65-68.
Ben-Nissan G., Vimer S., Warszawski S., Katz A., Yona M., Unger T., Peleg Y., Morgenstern D., Cohen-Dvashi H., Diskin R., Fleishman S. J. & Sharon M.
(2018).
Rapid characterization of secreted recombinant proteins by native mass spectrometry.
Communications Biology.
1:(1)
Cohen-Khait R., Dym O., Hamer-Rogotner S. & Schreiber G.
(2017).
Promiscuous Protein Binding as a Function of Protein Stability.
Structure (London, England : 1993).
25:(12)1867-1874.e3.
Milrot E., Shimoni E., Dadosh T., Rechav K., Unger T., Van Etten E. J. L. & Minsky A.
(2017).
Structural studies demonstrating a bacteriophage-like replication cycle of the eukaryote-infecting Paramecium bursaria chlorella virus-1.
PLoS Pathogens.
13:(8)
Bandyopadhyay B., Goldenzweig A., Unger T., Adato O., Fleishman S. J., Unger R. & Horovitz A.
(2017).
Local energetic frustration affects the dependence of green fluorescent protein folding on the chaperonin GroEL.
Journal of Biological Chemistry.
292:(50)20583-20591.
Dym O., Song W., Felder C., Roth E., Shnyrov V., Ashani Y., Xu Y., Joosten R. P., Weiner L., Sussman J. & Silman I.
(2016).
The impact of crystallization conditions on structure-based drug design: A case study on the methylene blue/acetylcholinesterase complex.
Protein Science.
25:(6)1096-1114.
Sun L., Xiong Y., Bashan A., Zimmerman E., Daube S. S., Peleg Y., Albeck S., Unger T., Yonath H., Krupkin M., Matzov D. & Yonath A.
(2015).
A Recombinant Collagen-mRNA Platform for Controllable Protein Synthesis.
ChemBioChem.
16:(10)1415-1419.
Sobolev V., Edelman M., Dym O., Unger T., Albeck S., Kirma M. & Galili G.
(2013).
Structure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesis.
Acta Crystallographica Section F-Structural Biology And Crystallization Communications.
69:(2)84-89.
Hama S., Soran H., Albeck S., Charlton-Menys V., Yadav R., Liu Y., France M., Tawfiq D. & Durrington P.
(2012).
High Paraoxonase-1 Hdl is More Effective Than Low Paraoxonase-1 Hdl in Impeding Ldl Oxidation in Vitro.
Atherosclerosis.
223:(2)529-529.
Carlessi R., Levin-Salomon V., Ciprut S., Bialik S., Berissi H., Albeck S., Peleg Y. & Kimchi A.
(2011).
GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling.
EMBO Reports.
12:(9)917-923.
Karanicolas J., Com J. E., Chen I., Joachimiak L. A., Dym O., Peck S. H., Albeck S., Unger T., Hu W., Liu G., Delbecq S., Montelione G. T., Spiegel C. P., Liu D. R. & Baker D.
(2011).
A De Novo Protein Binding Pair By Computational Design and Directed Evolution.
Molecular Cell.
42:(2)250-260.
Unger T., Dym O., Albeck S., Jacobovitch Y., Bernehim R., Marom D., Pisanty O. & Breiman A.
(2010).
Crystal structure of the three FK506 binding protein domains of wheat FKBP73: evidence for a unique wFK73_2 domain.
Journal of Structural and Functional Genomics.
11:(2)113-23.
Dym O., Albeck S., Peleg Y., Schwarz A., Shakked Z., Burstein Y. & Zimhony O.
(2009).
Structure-Function Analysis of the Acyl Carrier Protein Synthase (AcpS) from Mycobacterium tuberculosis.
Journal of Molecular Biology.
393:(4)937-950.
Levin K. B., Dym O., Albeck S., Magdassi S., Keeble A. H., Kleanthous C. & Tawfik D.
(2009).
Following evolutionary paths to protein-protein interactions with high affinity and selectivity.
Nature Structural & Molecular Biology.
16:(10)1049-U67.
Sharabi O., Peleg Y., Mashiach E., Vardy E., Ashani Y., Simian I., Sussman J. L. & Shifman J. M.
(2009).
Design, expression and characterization of mutants of fasciculin optimized for interaction with its target, acetylcholinesterase.
Protein Engineering Design & Selection.
22:(10)641-648.
Liberman N., Dym O., Unger T., Albeck S., Peleg Y., Jacobovitch Y., Branzburg A., Eisenstein M., Marash L. & Kimchi A.
(2008).
The Crystal Structure of the C-Terminal DAP5/p97 Domain Sheds Light on the Molecular Basis for Its Processing by Caspase Cleavage.
Journal of Molecular Biology.
383:(3)539-548.
Dym O., Albeck S., Unger T., Jacobovitch J., Branzburg A., Michael Y., Frenkiel-Krispin D., Wolf S. G. & Elbaum M.
(2008).
Crystal structure of the Agrobacterium virulence complex VirE1-VirE2 reveals a flexible protein that can accommodate different partners.
Proceedings of the National Academy of Sciences of the United States of America.
105:(32)11170-11175.
Albeck S., Dym O., Unger T., Snapir Z., Bercovich Z. & Kahana C.
(2008).
Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function.
Protein Science.
17:(5)793-802.
Goihberg E., Dym O., Tel-Or S., Shimon L., Frolow F., Peretz M. & Burstein Y.
(2008).
Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.
Proteins-Structure Function And Bioinformatics.
72:(2)711-719.
Peleg Y. & Unger T.
(2008).
Application of High-Throughput Methodologies to the Expression of Recombinant Proteins in E. coli.
.
197-208.
Fogg M. J., Alzari P., Bahar M., Bertini I., Betton J. -., Burmeister W. P., Cambillau C., Canard B., Carrondo M., Coll M., Daenke S., Dym O., Egloff M. -., Enguita F. J., Geerlof A., Haouz A., Jones T. A., Ma Q. & Manicka S. N.
(2006).
Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1196-1207.
Shao H., Revach M., Moshonov S., Tzuman Y., Gazit K., Albeck S., Unger T. & Dikstein R.
(2005).
Core promoter binding by histone-like TAF complexes.
Molecular and Cellular Biology.
25:(1)206-219.
Sandowski Y., Raver N., Gussakovsky E., Shochat S., Dym O., Livnah O., Rubinstein M., Krishna R. & Gertler A.
(2002).
Subcloning, expression, purification, and characterization of recombinant human leptin-binding domain.
Journal of Biological Chemistry.
277:(48)46304-46309.
Unger T., Oren Z. & Shai Y.
(2001).
The effect of cyclization of magainin 2 and melittin analogues on structure, function, and model membrane interactions: Implication to their mode of action.
Biochemistry.
40:(21)6388-6397.
Unger T., Juven-Gershon T., Moallem E., Berger M., Sionov R., Lozano G., Oren M. & Haupt Y.
(1999).
Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.
EMBO Journal.
18:(7)1805-1814.
Unger T., Sionov R., Moallem E., Yee C., Howley P., Oren M. & Haupt Y.
(1999).
Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.
Oncogene.
18:(21)3205-3212.
Mor F., Boccaccio G. & Unger T.
(1998).
Expression of autoimmune disease-related antigens by cells of the immune system.
Journal of Neuroscience Research.
54:(2)254-262.
Tamary H., Fromovich Y., Shalmon L., Reich Z., Dym O., Lanir N., Brenner B., Paz M., Luder A., Blau O., Korostishevsky M., Zaizov R. & Seligsohn U.
(1996).
Ala244Val is a common, probably ancient mutation causing factor VII deficiency in Moroccan and Iranian Jews.
Thrombosis and Haemostasis.
76:(3)283-291.
Fiscella M., Zambrano N., Ullrich S. J., Unger T., Lin D., Cho B., Mercer W. E., Anderson C. W. & Appella E.
(1994).
The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.
Oncogene.
9:(11)3249-57.
Mietz J. A., Unger T., Huibregtse J. M. & Howley P. M.
(1992).
The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein.
EMBO Journal.
11:(13)5013-20.
Unger T., Nau M. M., Segal S. & Minna J. D.
(1992).
p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer.
EMBO Journal.
11:(4)1383-90.
Unger T. & Shaul Y.
(1990).
The X protein of the hepatitis B virus acts as a transcription factor when targeted to its responsive element.
EMBO Journal.
9:(6)1889-1895.
Reichmann D., Rahat O., Albeck S., Meged R., Dym O. & Schreiber G.
().
The modular architecture of protein-protein binding interfaces.
Proceedings of the National Academy of Sciences of the United States of America.
102:(1)57-62.
Falini G., Albeck S., Weiner S. & Addadi L.
().
Control of aragonite or calcite polymorphism by mollusk shell macromolecules.
Science.
271:(5245)67-69.
Albeck S., Burstein Y., Dym O., Jacobovitch Y., Levi N., Meged R., Michael Y., Peleg Y., Prilusky J., Schreiber G., Silman I., Unger T. & Sussman J.
().
Three-dimensional structure determination of proteins related to human health in their functional context at the Israel Structural Proteomics Center (ISPC).
Acta Crystallographica Section D: Biological Crystallography.
61:(10)1364-1372.
Yifrach E., Holbrooksmith D., BüRgi J., Othman A., Eisenstein M., Roermund C. W., Visser W., Tirosh A., Rudowitz M., Bibi C., Galor S., Weill U., Fadel A., Peleg Y., Erdmann R., Waterham H. R., Wanders R. J. A., Wilmanns M., Zamboni N., Schuldiner M. & Zalckvar E.
().
Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions.
Molecular Systems Biology.
18:(9)
Peri L., Matzov D., Huxley D. R., Rainish A., Fierro F., Sapir L., Pfeiffer T., Waterloo L., HüBner H., Peleg Y., Gmeiner P., Mccormick P. J., Weikert D., Niv M. Y. & Shalev-Benami M.
().
A bitter anti-inflammatory drug binds at two distinct sites of a human bitter taste GPCR.
Nature Communications.
15.
Davidi D., Shamshoum M., Guo Z., Baron Y. M., Prywes N., Oz A., Jablonska J., Flamholz A., Wernick D. G., Antonovsky N., Pins B., Shachar L., Hochhauser D., Peleg Y., Albeck S., Sharon I., Muellercajar O. & Milo R.
().
Highly active rubiscos discovered by systematic interrogation of natural sequence diversity.
The EMBO Journal.
39:(18)
Peleg Y., Prabahar V., Bednarczyk D. & Unger T.
().
Harnessing the Profinity eXact™ System for Expression and Purification of Heterologous Proteins in E. coli.
.
33-43.
Bharat T. A. M., Zbaida D., Eisenstein M., Frankenstein Z., Mehlman T., Weiner L., Sorzano C. O. S., Barak Y., Albeck S., Briggs J. A. G., Wolf S. G. & Elbaum M.
().
Variable internal flexibility characterizes the helical capsid formed by agrobacterium VirE2 protein on single-stranded DNA.
Structure.
21:(7)1158-1167.
Israeli H., Degtjarik O., Fierro F., Chunilal V., Gill A. K., Roth N. J., Botta J., Prabahar V., Peleg Y., Chan L. F., Ben-Zvi D., Mccormick P. J., Niv M. Y. & Shalev-Benami M.
().
Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling.
Science.
372:(6544)808-814.
Sonawane P. D., Heinig U., Panda S., Gilboa N. S., Yona M., Kumar S. P., Alkan N., Unger T., Bocobza S., Pliner M., Malitsky S., Tkachev M., Meir S., Rogachev I. & Aharoni A.
().
Short-chain dehydrogenase/reductase governs steroidal specialized metabolites structural diversity and toxicity in the genus Solanum.
Proceedings of the National Academy of Sciences of the United States of America.
115:(23)E5419-E5428.
Bednarczyk D., Dym O., Prabahar V., Peleg Y., Pike D. H. & Noy D.
().
Fine Tuning of Chlorophyll Spectra by Protein-Induced Ring Deformation.
Angewandte Chemie-International Edition.
55:(24)6901-6905.
Frenkiel-Krispin D., Wolf S. G., Albeck S., Unger T., Peleg Y., Jacobovitch J., Michael Y., Daube S., Sharon M., Robinson C. V., Svergun D. I., Fass D., Tzfira T. & Elbaum M.
().
Plant transformation by Agrobacterium tumefaciens: Modulation of single-stranded DNA-VirE2 complex assembly by VirE.
Journal of Biological Chemistry.
282:(6)3458-3464.
Udi Y., Grossman M., Solomonov I., Dym O., Rozenberg H., Moreno V., Cuniasse P., Dive V., Arroyo A. G. & Sagi I.
().
Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody.
Structure.
23:(1)104-115.
Giannoulis A., Feintuch A., Unger T., Amir S. & Goldfarb D.
().
Monitoring the Conformation of the Sba1/Hsp90 Complex in the Presence of Nucleotides with Mn(II)-Based Double ElectronElectron Resonance.
Journal of Physical Chemistry Letters.
12:(51)12235-12241.
Smock R. G., Yadid I., Dym O., Clarke J. & Tawfik D.
().
De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints.
Cell.
164:(3)476-486.
Bandyopadhyay B. & Peleg Y.
().
Application of Restriction Free (RF) Cloning in Circular Permutation.
.
149-163.
Manicka S., Peleg Y., Unger T., Albeck S., Dym O., Greenblatt H. A., Bourenkov G., Lamzin V., Krishnaswamy S. & Sussman J.
().
Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12.
Proteins-Structure Function And Bioinformatics.
71:(4)2102-2108.
Cohen S., Albeck S., Ben-Dov E., Cahan R., Firer M., Zaritsky A. & Dym O.
().
Cyt1Aa toxin: Crystal structure reveals implications for its membrane-perforating function.
Journal of Molecular Biology.
413:(4)804-814.
Wein T., Millman A., Lange K., Yirmiya E., Hadary R., Garb J., Melamed S., Amitai G., Dym O., Steinruecke F., Hill A. B., Kranzusch P. J. & Sorek R.
().
CARD domains mediate anti-phage defence in bacterial gasdermin systems.
Nature.
639:(8055)727-734.
Lapidoth G., Khersonsky O., Lipsh R., Dym O., Albeck S., Rogotner S. & Fleishman S. J.
().
Highly active enzymes by automated combinatorial backbone assembly and sequence design.
Nature Communications.
9.
Unger T., Jacobovitch Y., Dantes A., Bernheim R. & Peleg Y.
().
Applications of the Restriction Free (RF) cloning procedure for molecular manipulations and protein expression.
Journal of Structural Biology.
172:(1)34-44.
SchüTz A., Bernhard F., Berrow N., Buyel J. F., Ferreira-Da-Silva F., Haustraete J., Van Den Heuvel J., Hoffmann J. E., De Marco A., Peleg Y., Suppmann S., Unger T., Vanhoucke M., Witt S. & Remans K.
().
A concise guide to choosing suitable gene expression systems for recombinant protein production.
STAR Protocols.
4:(4)
Yosef E., Katz A., Peleg Y., Mehlman T. & Karlish S. J.
().
Do Src kinase and caveolin interact directly with Na,K-ATPase?.
Journal of Biological Chemistry.
291:(22)11736-11750.
Heyne M., Shirian J., Cohen I., Peleg Y., Radisky E. S., Papo N. & Shifman J. M.
().
Climbing up and down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein-Protein Complexes.
Journal of the American Chemical Society.
143:(41)17261-17275.
Sberro H., Leavitt A., Kiro R., Koh E., Peleg Y., Qimron U. & Sorek R.
().
Discovery of Functional Toxin/Antitoxin Systems in Bacteria by Shotgun Cloning.
Molecular Cell.
50:(1)136-148.
Shaaltiel Y., Bartfeld D., Hashmueli S., Baum G., Brill-Almon E., Galili G., Dym O., Boldin-Adamsky S. A., Silman I., Sussman J. L., Futerman A. H. & Aviezer D.
().
Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system.
Plant Biotechnology Journal.
5:(5)579-590.
Alzari P. M., Berglund H., Berrow N. S., Blagova E., Busso D., Cambillau C., Campanacci V., Christodoulou E., Eiler S., Fogg M. J., Folkers G., Geerlof A., Hart D., Haouz A., Herman M. D., Macieira S., Nordlund P., Perrakis A., Quevillon-Cheruel S., Tarandeau F., Van Tilbeurgh H., Unger T., Luna-Vargas M., Velarde M., Willmanns M. & Owens R. J.
().
Implementation of semi-automated cloning and prokaryotic expression screening: The impact of SPINE.
Acta Crystallographica Section D: Biological Crystallography.
62:(10)1103-1113.
Osher E., Anis Y., Singer-Shapiro R., Urshanski N., Unger T., Albeck S., Bogin O., Weisinger G., Kohen F., Valevski A., Fattal-Valevski A., Sagi L., Weitman M., Shenberger Y., Sagiv N., Navon R., Wilchek M. & Stern N.
().
Treating late-onset Tay Sachs disease: Brain delivery with a dual trojan horse protein.
Molecular Therapy Methods and Clinical Development.
32:(3)
Fogg M. J., Alzari P., Bahar M., Bertini I., Betton J. M., Burmeister W. P., Cambillau C., Canard B., Carrondo M. A., Coll M., Daenke S., Dym O., Egloff M. P., Enguita F. J., Geerlof A., Haouz A., Jones T. A., Ma Q., Manicka S. N., Migliardi M., Nordlund P., Owens R. J., Peleg Y., Schneider G., Schnell R., Stuart D. I., Tarbouriech N., Unge T., Wilkinson A. J., Wilmanns M., Wilson K. S., Zimhony O. & Grimes J. M.
().
Erratum: Application of the use of high-throughput technologies to the determination of protein structures of bacterial and viral pathogens (Acta Crystallographica Section D: Biological Crystallography (2006) D62 (1196-1207)).
Acta Crystallographica Section D: Biological Crystallography.
62:(12)1571.
Erijman A., Dantes A., Bernheim R., Shifman J. M. & Peleg Y.
().
Transfer-PCR (TPCR): A highway for DNA cloning and protein engineering.
Journal of Structural Biology.
175:(2)171-177.
Pokorna S., Khersonsky O., Lipsh-Sokolik R., Goldenzweig A., Nielsen R., Ashani Y., Peleg Y., Unger T., Albeck S., Dym O., Tirosh A., Tarayra R., Hocquemiller M., Laufer R., Ben-Dor S., Silman I., Sussman J. L., Fleishman S. J. & Futerman A. H.
().
Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification.
FEBS Journal.
290:(13)3383-3399.
Li M., Greenblatt H. M., Dym O., Albeck S., Pais A., Gunanathan C., Milstein D., Degani H. & Sussman J.
().
Structure of estradiol metal chelate and estrogen receptor complex: The basis for designing a new class of selective estrogen receptor modulators.
Journal of Medicinal Chemistry.
54:(10)3575-3580.
Tarayrah-Ibraheim L., Maurice E. C., Hadary G., Ben-Hur S., Kolpakova A., Braun T., Peleg Y., Yacobi-Sharon K. & Arama E.
().
DNase II mediates a parthanatos-like developmental cell death pathway in Drosophila primordial germ cells.
Nature Communications.
12:(1)
Wong E., Cohen T., Romi E., Levin M., Peleg Y., Arad U., Yaron A., Milla M. E. & Sagi I.
().
Harnessing the natural inhibitory domain to control TNF alpha Converting Enzyme (TACE) activity in vivo.
Scientific Reports.
6.
Baran D., Pszolla M. G., Lapidoth G. D., Norn C., Dym O., Unger T., Albeck S., Tyka M. D. & Fleishman S. J.
().
Principles for computational design of binding antibodies.
Proceedings of the National Academy of Sciences of the United States of America.
114:(41)10900-10905.
Mock B., Givol D., Dhoostelaere L., Huppi K., Seldin M., Gurfinkel N., Unger T., Potter M. & Mushinski J.
().
Mapping of the bcl-2 oncogene on mouse chromosome 1.
Cytogenetics and Cell Genetics.
47:(1-2)11-15.
Reichmann D., Cohen M., Abramovich R., Dym O., Lim D., Strynadka N. C. J. & Schreiber G.
().
Binding Hot Spots in the TEM1-BLIP Interface in Light of its Modular Architecture.
Journal of Molecular Biology.
365:(3)663-679.
Gould N. L., Scherer G. R., Carvalho S., Shurrush K., Kayyal H., Edry E., Elkobi A., David O., Foqara M., Thakar D., Pavesi T., Sharma V., Walker M., Maitland M., Dym O., Albeck S., Peleg Y., Germain N., Babaev I., Sharir H., Lalzar M., Shklyar B., Hazut N., Khamaisy M., LéVesque M., Lajoie G., Avoli M., Amitai G., Lefker B., Subramanyam C., Shilton B., Barr H. & Rosenblum K.
().
Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimers disease phenotype in mice.
Journal of Clinical Investigation.
133:(19)
Yadid I., Kirshenbaum N., Sharon M., Dym O. & Tawfik D.
().
Metamorphic proteins mediate evolutionary transitions of structure.
Proceedings of the National Academy of Sciences of the United States of America.
107:(16)7287-7292.
Yifrach E., Rudowitz M., Cruz-Zaragoza L. D., Tirosh A., Gazi Z., Peleg Y., Kunze M., Eisenstein M., Schliebs W., Schuldiner M., Erdmann R. & Zalckvar E.
().
Determining the targeting specificity of the selective peroxisomal targeting factor Pex9.
Biological Chemistry.
404:(2-3)121-133.
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Amalgam, an axon guidance Drosophila adhesion protein belonging to the immunoglobulin superfamily: Over-expression, purification and biophysical characterization.
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Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59.
Proceedings of the National Academy of Sciences of the United States of America.
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SPINE bioinformatics and data-management aspects of high-throughput structural biology.
Acta Crystallographica Section D-Structural Biology.
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Erratum: Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces (PLoS Computational Biology(2019)15: 8(e1007207)Doi: 10.1371/journal.pcbi.1007207).
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His-tag based supramolecular biopolymerization.
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Stable Mammalian Serum Albumins Designed for Bacterial Expression.
Journal of Molecular Biology.
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Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the ke07 series.
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Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression.
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Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism.
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Integration of bacterial lytic polysaccharide monooxygenases into designer cellulosomes promotes enhanced cellulose degradation.
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The intrinsic protein flexibility of endogenous protease inhibitor TIMP-1 controls its binding interface and affects its function.
Biochemistry.
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Expression of the bcl2 gene in mouse B lymphocytic cell lines is differentiation stage specific.
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Acta Crystallographica Section D: Biological Crystallography.
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The identification and characterization of an oxalyl-CoA synthetase from grass pea ( Lathyrus sativus L.).
RSC Chemical Biology.
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Cortactin releases the brakes in actin- based motility by enhancing WASP-VCA detachment from Arp2/3 branches.
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The human interferon receptor: NMR-based modeling, mapping of the IFN-α2 binding site, and observed ligand-induced tightening.
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Chemical Science.
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Efficient targeted degradation via reversible and irreversible covalent PROTACs.
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The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
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Eukaryotic expression: Developments for structural proteomics.
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