We are a new lab working on cancer genome evolution, chromosome biology, and therapy resistance. We are always looking for curious and motivated students/postdocs to join.
Our lab studies how catastrophic numerical and structural chromosome aberrations are formed in cancer. Such chromosome defects are found in the majority of human tumors and are strong drivers of cancer initiation, growth, metastasis, and therapy resistance. By understanding the underlying mechanisms of chromosome alterations, we aim to identify targetable vulnerabilities to be used for novel therapy design.
We are currently looking for an enthusiastic postdoc to study how genetic mutations and amplifications cooperate in human cancers to drive therapy resistance.
The work will involve both computational and experimental biology approaches, including molecular biology, cell and tissue culture, confocal microscopy, and DNA/RNA sequencing. Candidates should have a very strong background in analyzing DNA sequencing data to study mutations and structural variations, including from public databases such as TCGA.
If you are interested, please contact Ofer at ofer.shoshani@weizmann.ac.il