Research

Pattern-generating fluorescent molecular probes

Cross-reactive sensor arrays, also known as chemical, optical, or electronic noses/tongues, are analytical devices that differentiate various analytes based on unique fingerprints generated by nonspecific sensors or receptors within the array.

Artificial protein crosstalk

In recent years, much interest has been devoted to developing artificially activated enzymes. The motivation for developing such systems lies in their potential applications across various research fields, such as sensing, artificial biology, catalyst development, and therapy.

Chemically modified bacteria

Cell surface engineering using chemical tools is a pivotal approach in modern biology, enabling precise modifications of cell membranes to study, control, and enhance cellular functions, as well as to endow cells with novel, unnatural properties.

Targeting and sensing cell surface proteins

Cell surface proteins (CSPs) are an important class of disease biomarkers and represent a key category of drug targets. Building on our previous work in developing turn-on probes for protein detection, we are advancing novel CSP-targeting probes for both diagnostic and therapeutic applications.