For the preparation of vitrified fluid samples or extremely thin samples for cryo-TEM, including biological suspensions and industrial emulsions in both aqueous and inorganic (non-toxic) solvents.

The Leica EM GP plunge freezes samples into liquid ethane after removing excess fluid by automatic blotting from one side of the sample. Prior to freezing, the sample is maintained in a temperature and humidity controlled environmental chamber, adjustable between +4°C and +60°C and room humidity to 99 %.

The EM GP can be used to vitrify samples not only on EM grids, but also sapphire discs and samples in freeze fracture planchettes.