Instrumentation

High Pressure Freezing machine

High Pressure Freezing immobilizes aqueous samples in their native state to deliver rapid sample preservation without introducing significant structural alterations.

• One move, fully automated specimen loading: The cartridge assembly and the…

The freeze fracture technique is used as a complementary technique to direct imaging by cryo-TEM, especially for viscous systems, systems containing micron-scale objects as well as cells, tissues and microorganisms which are too thick for plunge freezing (roughly >5-10 µm.)…

For the preparation of vitrified fluid samples or extremely thin samples for cryo-TEM, including biological suspensions and industrial emulsions in both aqueous and inorganic (non-toxic) solvents.

The Leica EM GP plunge freezes samples into liquid ethane after removing excess…

An automated plunging system for vitrifying TEM grids for cryo-EM applications. Good vitrification is a crucial step within structural biology applications such as single particle analysis (SPA), cryo electron tomography (cryo-ET), and MicroED. The Thermo Scientific Vitrobot Mark…

• Freeze Substitution and Low-Temperature Embedding System for Light and Electron Microscopy.
• The Leica EM AFS2 performs freeze substitution and progressive lowering of temperature (PLT) techniques and allows low temperature embedding and polymerization of resins.
• The Leica EM…

The Ultramicrotome Leica EM UC7 provides easy preparation of semi- and ultrathin sections as well as smooth surfaces of biological and industrial samples for TEM, SEM, AFM and LM examination.

• Sectioning at room temperature as well as cryogenic temperatures.
• Eucentric…

Microwave processing system

The PELCO BioWave Pro+ is a versatile microwave system designed for laboratory use in sample preparation for electron and light microscopy, immunological/confocal/in situ staining/decalcification and tissue fixation.

• Enhanced processing of tissue…

The Leica EM TP is an instrument used for fixation and dehydration of samples for further treatment. It can be used for resin processing for electron microscopy (EM) and light microscopy (LM). The Leica EM TP consists of a base unit onto which an EM or LM processing outfit can be…

The vibrating blade microtome is used to produce monolayer or thick sections of fixed or fresh tissue under physiological conditions without freezing or embedding.

At the EM Unit the device is used mostly for preparing sections of agarose embedded, fixed or unfixed samples for…

• High vacuum sputter and carbon coater.
• A compact, fully automatic sputter coater and/or carbon coater.
• The use of an oil-free, pumping system reduces contamination or defects in the coating to a minimum.
• The device can be kept under vacuum when switched off. This…

The PELCO easiGlow™ Glow Discharge Cleaning System is a compact, quick and easy to use standalone system. It is primarily designed for cleaning TEM grids and hydrophilization of TEM carbon support films, which have the tendency to be hydrophobic. A glow discharge treatment with…

• Decontaminate specimens and columns of SEMs and FIBs. The Evactron® CombiClean™ System combines an onboard vacuum cleaning chamber and external PRS (Plasma Radical Source) control in one unified system.
• Cleans SEM/TEM samples and SEM chambers from one desktop controller
• Store…