Leveraging single cell technologies to engineer the immune system

Lecturer Prof. Ido Amit

new frontiers in human somatic evolution – from single cells to large cohorts

Lecturer Prof. Dan Landau

Spatiotemporal perspectives on tumor growth with single cell genomics

Lecturer Prof. Nir Yosef

Chemical Protein Synthesis and Modification: Excellent Tools for Therapeutic Applications

Lecturer Prof. Norman Metanis

PKC-eta promotes breast cancer metastasis by regulating the Hippo–YAP signaling pathway

Lecturer Liju Vijaya Steltar

Unleashing natural IL-18 activity using an anti-IL-18BP blocker antibody induces potent immune stimulation and anti-tumor effects

Lecturer Dr. Assaf Menachem

Proteolysis-driven immunity: New insights into the role of proteasome-cleaved peptides in adaptive

Lecturer Prof. Yifat Merbl

Towards the theory of everything- microbiome version

Lecturer Prof. Eran Elinav

Challenges in CAR T cell therapy in hematologic malignancies and beyond

Lecturer Prof. Elad Jacoby

Deciphering molecular heterogeneity in tumors with increased EGFR expression towards -individualized treatments

Lecturer Dr. Maria Jubran-Khoury, DMD, PhD

Tumor Innervation as a Novel Therapeutic Target

Lecturer Prof. Ronny Drapkin

Apoptotic Pathways as Molecular Switches of Tumor Initiation and Reversion

Lecturer Prof. Sarit Larisch

Lung cancer – advances in recent years and the role of B-cells in immune response

Lecturer Prof. Jair Bar

Can one bug do it? - from the gut microbiome to anti-tumor immunity

Lecturer Prof. Ze’ev Ronai

Can one bug do it? - from the gut microbiome to anti-tumor immunity

Lecturer Prof. Zeev Ronai

The Digital Transformation of Pathology: Opportunities and Challenges for Cancer Research

Lecturer Hanni Naor

The Digital Transformation of Pathology: Opportunities and Challenges for Cancer Research

Lecturer Dr/ Nir Pilar

Genetic analysis of breast cancer in the mouse mammary gland

Lecturer Prof. Sean Egan

Unleashing natural IL-18 activity using an anti-IL-18BP blocker antibody induces potent immune stimulation and anti-tumor effects

Lecturer Dr. Assaf Menachem

From suppressive to active—rewiring the head and neck cancer microenvironment for durable checkpoint response

Lecturer Prof. Moshe Elkabets, Ph.D

In vivo targeted and deterministic single cell cancer induction

Lecturer Prof. David Bensimon

A Deep Dive into Immune Tolerance

Lecturer Dr. Ranit Kedmi

Functional genomic approaches to cancer

Lecturer Prof. Todd Golub

Cytokines and soluble inhibitors: interleukin-18 binding protein for clinical use

Lecturer Prof. Soohyun Kim

Host-Microbiome Interaction in Health and Disease

Lecturer Prof. Eran Elinav

The protective role of physical activity on melanoma brain metastases

Lecturer Prof. Carmit Levy

Towards fast and accessible precision oncology directly from the good old histopathology slides

Lecturer Dr. Eytan Ruppin

Breaking New Methodologies in Biomedical Research

Leveraging single cell technologies to engineer the immune system

Lecturer Prof. Ido Amit

Beyond protein degradation: proteolysis-driven immunity

Lecturer Prof. Yifat Merbl

Modeling and Modulating Antitumor Immunity with Precision Nanomedicines in 3D-Bioprinted Tumoroids

Lecturer Prof. Ronit Satchi-Fainaro

Evolution of the pathogenic mold Aspergillus fumigatus on voriconazole identifies novel resistance genes

Lecturer Dr. Mariana Handelman

Stress and mutation dependencies in the tumor microenvironment

Lecturer Prof. Ruth Scherz-Shouval

Cancer aneuploidy: From evolutionary pressures to cellular vulnerabilities

Lecturer Prof. Uri Ben-David

Targeting leukemia cell vulnerabilities with our experimental new drug

Lecturer Prof. Yinon Ben-Neriah

EARLY-ONSET GI CANCER – AN EVOLVING ENTITY

Lecturer Prof. Irit Ben-Aharon MD, PhD

Pathways Regulating Neutrophil Function in Cancer.

Lecturer Prof. Zvika Granot

Molecular principles underlying aggressive cancers

Lecturer Dr. Ruth Nussinov

Regulation of immune cell function in tumor microenvironment of triple-negative breast cancer

Lecturer Prof. Idit Shachar

Spatial transcriptomics of pancreatic cancer development and immune cells targeting to restrict tumor growth

Lecturer Dr. Oren Parnas

The expanding world of PD-L1 activities and regulation in breast cancer – N-linked glycosylation and beyond

Lecturer Prof. Adit Ben-Baruch

Leveraging single cell technologies to engineer the immune system

Lecturer Prof. Ido Amit

Spatial Analysis of Development and Cancer

Ubiquitin, cell identity and cancer

Lecturer Prof. Amir Orian MD/PhD

Immunological aspects of immune checkpoint blockade

Lecturer Prof. Yuval Shaked

Glioma cellular heterogeneity in time and space

Lecturer Prof. Itay Tirosh

Insights from germline and somatic replication repair deficiency on cancer initiation and immunotherapy

Lecturer Prof. Uri Tabori

ESR1 mutations: From Discovery to Clinical Practice

Lecturer Dr. Rinath Jeselsohn

New STATs on proteasome-mediated tumor inflammation

Lecturer Prof. Yifat Merbl

A DNA methylation atlas of normal human cell types

Lecturer Prof. Tommy Kaplan

Melanosomes as cancer immune modulators

Lecturer Prof. Carmit Levy

The Golden Approach for Overcoming Bio-Barriers: Delivering Nanomedicine to Brain and Beyond

Lecturer Prof. Rachela Popovtzer

The roles of RNA processing in cancer initiation and progression and its modulation for cancer therapy

Lecturer Prof. Rotem Karni

Highly multiplexed imaging of tissues with subcellular resolution by imaging mass cytometry

Lecturer Prof. Bernd Bodenmiller

Nucleo-cytoplasmic shuttling of the 26 proteasome: A potential anti-cancer drug target and prognostic biomarker

Lecturer Prof. Aaron Ciehanover Ido Livneh

Amino acid substitutants, cancer development, and anti-tumor immunity

Lecturer Prof. Reuven Agami

p53: not just a cell-autonomous tumor suppressor

Lecturer Prof. Moshe Oren

Next-generation antibody-based cancer immunotherapies

Lecturer Prof. Rony Dahan

Dissecting the immune-controlled signaling networks driving breast cancer progression

Lecturer Dr. Merav Cohen

Regulation of the epithelial control gene p63 by oncogenes and the Hippo signaling pathway

Lecturer Prof. Ron M. Prywes

The Tumor Suppressors Scribble and Lgl regulators of cell polarity

Lecturer Dr. Maha Abedrabbo

Metabolic rewiring driving metastasis formation

Lecturer Prof. Sarah-Maria Fendt

Metastases are just a touch away: Thin membranous connections (TMCs) between tumor cells and macrophages promote tumor cell extravasation

Lecturer Dr. Alessandro Genna

The safety pharmacology of Syk inhibitors: Cardiovascular complications resulting from off-target tyrosine kinase inhibition

Lecturer Ms. Marieke Van Daele

Phosphoinositide switches at the cytokinetic bridge control abscission, senescence and cellular ploidy

Lecturer Prof. Emilio Hirsch

Microbiota and cancer treatment - an ecological journey

Lecturer Dr. Ben Boursi

Tumor intrinsic immunity: Mismatch repair deficiency as a model

Lecturer M.D.,Prof. Luis A. Diaz

Beyond Darwin: understanding cancer persister cells

Lecturer Dr. Yaara Oren

Drivers and dependencies arising during tumor evolution

Lecturer Prof. Kris Wood

Somatic mutation in normal tissues

Lecturer Dr. Inigo Martincorena

Stromal and immune plasticity shape the metastatic microenvironment

Lecturer Prof. Neta Erez

Innovations in Interventional Oncology: From Benchtop to Clinic

Lecturer Prof. Stephen Solomon

The mitochondrial gatekeeper VDAC1 as an emerging drug target for novel anti-cancer therapeutics

Lecturer Prof. Varda Shoshan-Barmatz

Unraveling Heterotypic Cell Interactions and Cell Identity Transitions in Chronic Inflammation-Driven Intrahepatic Cholangiocarcinoma

Lecturer Prof. Eli Pikarsky

Drug delivery systems in the treatment of cancer: Fundamentals and clinical applications

Lecturer Dr. Avi Schroeder

Turning immune “cold” into immune “hot” tumors by reverting the tumor microenvironment into hostile to the cancer cells.

Lecturer Prof. Avigdor Scherz

Autotaxin in the tumor microenvironment: from discovery to metastasis and immune evasion

Lecturer Prof. Wouter Moolenaar

Reprogramming Macrophages using Early Apoptotic Cellular Therapy Against Peritoneal Solid Tumor

Lecturer Prof. Dror Mevorach

Circulating tumor cells

Lecturer Prof. Nicola Aceto

Sensitizing P-selectin-expressing brain malignancies to immune checkpoint modulators

Lecturer Prof. Ronit Satchi-Fainaro, PhD

Genetic and Epigenetic Drivers of Melanoma Formation and Progression

Lecturer Marcus Bosenberg, MD, PhD

Epigenetic Liquid Biopsy

Lecturer Prof. Yuval Dor

MAPPING PATHS OF TUMOR EVOLUTION WITH SINGLE-CELL PHYLOGENETICS

Lecturer Prof. Nir Yosef

Non-coding RNAs as determinants of breast cancer progression

Lecturer Prof. Giovanni Blandino

The power of ONE: Immunology in the age of single cell genomics

Lecturer Prof. Ido Amit

Computational approaches for identifying genomic and metabolic predictors of cancer patient response to immune checkpoint blockade therapy

Lecturer Dr. Keren Yizhak

Using genomics to investigate radiation-related thyroid cancer following the Chernobyl accident in 1986

Lecturer M.D.,Stephen J. Chanock

Large scale spatio-temporal organization of brain tumors: from oncostreams to liquid crystals

Lecturer Prof. Pedro Lowenstein

Reprograming T cell immunity to enhance immunotherapy: from protein engineering to bedside

Lecturer Prof. Cyrille Cohen

Host pro-tumorigenic response to anti-cancer therapies: the role of the ECM

Lecturer Prof. Yuval Shaked

Interferon signaling is associated with chemoresistance in triple-negative breast cancer

Lecturer Prof. Stefan Wiemann

Memory NK cells in Cancer Immunotherapy

Lecturer Prof. Inpyo Choi

mRNA Vaccines and Therapies

Lecturer Prof. Ugur Sahin

Single-molecule and single-cell epigenetics: Decoding the epigenome for cancer research and diagnostics

Lecturer Prof. Efrat Shema

Next-generation transcriptomics-based precision oncology

Lecturer Dr. Eytan Ruppin

The Tumor Ecosystem – Evolution of a Concept

Lecturer Prof. Isaac P. Witz

Cellular Plasticity in Cancer

Mechanisms driving genome catastrophes in cancer

Lecturer Dr. Ofer Shoshani

Mechanisms of cancer protection in congenital IGF1 deficiencies

Lecturer Prof. Haim Werner

Metabolism, diet, and cancer

Lecturer Joshua Rabinowitz, MD, PhD

Targeting metabolic vulnerabilities in cancer

Lecturer Prof. Tomer Shlomi

HOST MICRO BIOME INTERACTIONS IN HEALTH AND DISEASE

Lecturer Prof. Eran Elinav, M.D., Ph.D.

Killing Cancer Stem Cells

Lecturer Jeremy Rich, MD, MHS, MBA

Insights on hypermutation in cancer initiation and response to immunotherapy. Lessons from a rare cancer syndrome

Lecturer Prof. Uri Tabori

The microbiome as part of the tumor ecosystem

Lecturer Prof. Ravid Straussman

Canceled ! - The microbiome as part of the tumor ecosystem

Lecturer Prof. Ravid Straussman

Intravital microscopy of the protection mechanisms that clear mutations in intestinal and breast tissues

Lecturer Prof. Jacco van Rheenen

Tumor ecosystems- from prediction to modelling.

Lecturer Prof. Carlos Caldas

Skin stem cells in tissue regeneration and tumor formation

Lecturer Prof. Yaron Fuchs

Cancer is a disease of epigenetic stochasticity

Lecturer Prof. Andrew(Andy) Feinberg

BOOSTING CAR T CELL EFFICACY BY MODULATION OF THE MICROENVIRONMENT IN BRAIN TUMORS

Lecturer Prof. Dinorah Friedmann-Morvinski

Dissecting tumor heterogeneity in glioma

Lecturer Prof. Itay Tirosh

At the crossroads of science, engineering, and medicine: Improving cancer diagnosis

Lecturer Prof. Yonina Eldar & Keren Peri-Hanania, MD

Antibody-mediated immune responses in ovarian cancer patients

Lecturer Prof. Ziv Shulman

Melanoma addiction to GCDH defines NRF2 tumor suppressor function

Single cell approaches for studying spatial heterogeneity in the healthy and malignant liver.

Lecturer Prof. Shalev Itzkovitz

Aging, the Oncometabolite Methylmalonic Acid, and Metastasis

Lecturer Prof. John Blenis, Ph.D.

Modeling and targeting cancer aneuploidy

Lecturer Prof. Uri Ben-David

SCANnTREAT: photodynamic therapy triggered by spectral scanner CT: an new tool for cancer treatment?

Lecturer Prof. Philippe DOUEK

A tale of four tales and more

Lecturer Prof. Eytan Ruppin

Love the neighbor – Unraveling the tumor microenvironment using multiplexed imaging

Lecturer Dr. Leeat Keren

The Next Frontier in Genetic Medicine: mRNA-Based Approach For Treating Diseases

Lecturer Prof. Lior Zangi

Single Cell Atlases as Roadmaps in Pediatric Cancer

Lecturer Prof. Aviv Regev

The success and challenges of introducing PARP inhibitors into the therapy of ovarian cancer- a clinician’s perspective

Lecturer Prof. Jonathan A Ledermann BSc MD FRCP FMedSci

GOING TO EXTREMES: STUDIES WITH RARE EXCEPTIONAL SURVIVORS OF OVARIAN CANCER.

Lecturer Prof. David Bowtell

New Experimental Methods in Cancer Research - Workshop

Breast tumor evolution

Lecturer Prof. Kornelia Polyak

The two faces of NF-ĸB – the ‘canonical’ tumor promoter and the ‘non-canonical’ tumor suppressor

Lecturer Prof. Aaron Ciechanover

Therapeutic Exploitation of Metabolic Vulnerabilities of Cancer

Lecturer Prof. Eyal Gottlieb

Inactivation of DNA repair and high dose Vitamin C boost cancer immunotherapy

Lecturer Prof. Alberto Bardelli

VEGF/vascular-centered view of the tumor microenvironment and aging

Lecturer Prof. Eli Keshet

RNA Therapeutics: From Gene Silencing to Gene Editing

Lecturer Dan Peer, PhD

Inflammation, Metabolism and Immunity in Liver Cancer: From Pathogenesis to Treatment

Lecturer Dr. Michael Karin

Proteasome profiling meets precision oncology

Lecturer Prof. Yifat Merbl

Targeted protein degradation for the treatment of cancer

Lecturer Benjamin Ebert, MD, PhD

Studying resistance in cancer

Lecturer Prof. Getz Gad

Molecular mechanisms of senescence on the crossroads of cancer and aging

Lecturer Prof. Valery Krizhanovsky

Stromal dynamic plasticity shapes the microenvironment in breast cancer metastasis

Lecturer Prof. Neta Erez, PhD

The brain as a central regulator of immunity

Lecturer Prof. ASYA ROLLS

Cancer evolution, immune evasion and metastasis

Lecturer Prof. Charles Swanton MD PhD FMedSci FRS

BRCA mutations rewire stromal cells in the tumor microenvironment

Lecturer Prof. Ruth Scherz-Shouval

Effects of p16Ink4a and cellular senescence on tissue function and cancer development

Lecturer Prof. Ittai Ben-Porath

Tumor exosome biomarkers for early cancer detection

Lecturer David Lyden MD, PhD

Deciphering the immunogenomic landscape in melanoma

Lecturer Prof. Yardena Samuels

TP53 mutations playing Dr. Jekyll and Mr. Hyde in the mouse gut

Lecturer Prof. Yinon Ben-Neriah

The power of ONE: Immunology in the age of single cell genomics

Lecturer Prof. Ido Amit

A new dawn for eosinophils in the tumor microenvironment

Lecturer Prof. Ariel Munitz

NK cells in Cancer: The next Breakthrough?