We employ state-of-the-art technologies for our studies. Our advanced in-vitro equipment, including anaerobic chambers and organoid cultures, complimented by in-vivo facilities, such as germ-free animal housing, and robotic high-throughput modalities for metagenomic and epigenomic next-generation sequencing and analysis, enable in-depth elucidation of the molecular and genetic mechanisms underlying host-microbial interactions at the organism level.
In addition, we use novel transgenic mice in a multitude of animal models for human disease. Using a combination of these technologies, we aim at deciphering the molecular "language" of communication between the host and the microbiota in order to exploit this language for the development of personalized approaches to treating common idiopathic diseases.