Pages

תוצאות חיפוש לאירועים

  • Date:03שנימרץ 2025

    Exploring RNA and protein folding with Single-Molecule Force Spectroscopy

    More information
    שעה
    11:00 - 12:15
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Matthias Rief
    דף בית
    תקצירShow full text abstract about <p>Single-molecule force spectroscopy (SMFS) enables h...»
    <p>Single-molecule force spectroscopy (SMFS) enables high-resolution insights into the kinetics and mechanisms of biomolecular interactions. In this talk, I will present how SMFS, helps uncover key principles in nucleic acid and protein folding. Examples discussed will include the microsecond invasion kinetics of toehold-mediated strand displacement (TMSD) of DNA and RNA as well as mRNA-Roquin interactions, which regulate mRNA degradation via specific 3’UTR hairpin structures.&nbsp;Finally, we study chaperone-mediated unfolding of the glucocorticoid receptor (GR), demonstrating how Hsp70/Hsp40 unfolds GR in discrete ATP-driven steps, stabilizing novel intermediates and acting as an unfoldase. These studies showcase SMFS as a powerful tool to resolve biomolecular dynamics providing new insights into RNA structure-function relationships and chaperone-mediated protein regulation.</p>
    סימפוזיונים
  • Date:04שלישימרץ 2025

    The 4th International Day of Women in Science

    More information
    שעה
    08:30 - 16:00
    כותרת
    The 4th International Day of Women in Science
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    יושב ראש
    Idit Shachar
    דף בית
    צרו קשר
    כנסים
  • Date:04שלישימרץ 2025

    "Cut it Out" – Lytic Cell Death and Inflammation Mediated by the “NINJA” Protein – NINJ1

    More information
    שעה
    14:00 - 15:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהDr. Liron David
    מארגן
    המחלקה לביולוגיה מבנית וכימית
    הרצאה
  • Date:05רביעימרץ 2025

    students seminar series- Azrieli

    More information
    שעה
    10:30 - 12:30
    מיקום
    בניין קמיליה בוטנאר
    צרו קשר
    הרצאה
  • Date:05רביעימרץ 2025

    students seminar series- Azrieli

    More information
    שעה
    10:30 - 12:30
    מיקום
    בניין קמיליה בוטנאר
    צרו קשר
    הרצאה
  • Date:06חמישימרץ 2025

    LSCF departmental seminar by Dr. Yoav Peleg & Prof. Moran Shalev-Benami

    More information
    שעה
    09:00 - 10:00
    מיקום
    Candiotty Auditorium
    מרצהDr. Yoav Peleg, Prof. Moran Shalev-Benami
    מארגן
    המחלקה לתשתיות מחקר מדעי החיים
    הרצאה
  • Date:09ראשוןמרץ 2025

    On Light Propagation in Clouds and Light Flashes Above Clouds: Two Crazy Ideas, Two New Models

    More information
    שעה
    11:00 - 12:00
    מיקום
    בניין משפחת זוסמן
    M. Magaritz room
    מרצהCarynelisa Haspel
    צרו קשר
    תקצירShow full text abstract about <p>In this seminar, two new models will be presented. ...»
    <p>In this seminar, two new models will be presented. The first new model is a first-principles description of the propagation of light in a cloud, based on a classical solution to Maxwell's equations rather than radiative transfer theory. The second new model is a fully three-dimensional, time-dependent model of the regions of possible sprite inception in the mesosphere, based on the classical method of images from electrostatics rather than finite differencing in space. The reason why each model is unique, the problems each model can solve, and the kinds of results each model can produce will be discussed</p>
    הרצאה
  • Date:09ראשוןמרץ 2025

    On Light Propagation in Clouds and Light Flashes Above Clouds: Two Crazy Ideas, Two New Models

    More information
    שעה
    11:00 - 12:00
    מיקום
    בניין משפחת זוסמן
    M. Magaritz seminar room
    מרצהCarynelisa Haspel
    צרו קשר
    תקצירShow full text abstract about <p>In this seminar, two new models will be presented. ...»
    <p>In this seminar, two new models will be presented. The first new model is a first-principles description of the propagation of light in a cloud, based on a classical solution to Maxwell's equations rather than radiative transfer theory. The second new model is a fully three-dimensional, time-dependent model of the regions of possible sprite inception in the mesosphere, based on the classical method of images from electrostatics rather than finite differencing in space. The reason why each model is unique, the problems each model can solve, and the kinds of results each model can produce will be discussed.&nbsp;&nbsp;</p>
    הרצאה
  • Date:11שלישימרץ 2025

    A Vascular-Centered View on Aging, Regeneration and Rejuvenation

    More information
    שעה
    12:30 - 13:30
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    Auditorium
    מרצהProf. Eli Keshet
    מארגן
    המחלקה לאימונולוגיה ורגנרציה ביולוגית
    צרו קשר
    הרצאה
  • Date:11שלישימרץ 2025

    What is special about activity in the basal ganglia?

    More information
    שעה
    12:30 - 14:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Mati Joshua
    מארגן
    המחלקה למדעי המוח
    צרו קשר
    תקצירShow full text abstract about <p>There are two major classes of theories about the b...»
    <p>There are two major classes of theories about the basal ganglia. The first class hypothesizes</p><p>that the basal ganglia are the site where cortical sensorimotor and dopaminergic reward</p><p>information interact to potentiate and select actions. These theories predict that content</p><p>specificity of information emerges from within the basal ganglia. The second class of</p><p>theories posits that information is manipulated within the basal ganglia through processes</p><p>such as dimensionality reduction. These theories are primarily based on the fact that there</p><p>is a large reduction in the number of neurons from the input to the output stages of the basal</p><p>ganglia. These theories posit that there are changes in the coding properties of neurons</p><p>rather than the emergence of content specificity.</p><p>In this talk, I will present a set of studies where we analyzed the eye movement system of</p><p>monkeys to compare single-neuron activity in the basal ganglia with activity in the</p><p>cerebellum and the frontal cortex. We used tasks that manipulated both eye movements</p><p>and expected rewards. We found that rather than coding specific sensorimotor or reward</p><p>parameters, the basal ganglia were unique in how they coded these parameters, both in</p><p>terms of the signal-to-noise ratio of responses and in the variety of their temporal patterns.</p><p>These results strongly suggest that the basal ganglia play a role in manipulating rather than</p><p>generating reward and sensorimotor signals.</p>
    הרצאה
  • Date:12רביעימרץ 2025

    Birthday hormone: the neuroendocrine control of hatching in fish

    More information
    שעה
    10:00 - 11:00
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    Botnar Auditorium
    מרצהDr. Matan Golan
    צרו קשר
    הרצאה
  • Date:13חמישימרץ 2025

    Synthetic biology platforms for biomedical applicationsnnounced

    More information
    שעה
    15:00 - 16:00
    מיקום
    Leon Benoziyo for Biological Sciences
    Auditorium Rm.191
    מרצהDr. Lior Nissim
    The Faculty of Medicine - Hebrew University of Jerusalem
    הרצאה
  • Date:16ראשוןמרץ 2025

    EPScon 2025 - The 14th Students' Conference for Earth and Planetary Sciences

    More information
    שעה
    08:00 - 08:00
    מיקום
    מרכז כנסים על-שם דויד לופאטי
    יושב ראש
    Adam Chaikin Lifshitz
    כנסים
  • Date:18שלישימרץ 2025

    Vascular Aging:

    More information
    שעה
    11:00 - 12:00
    כותרת
    The Hidden Driver of Age-Related Organ Dysfunction
    מיקום
    בניין ארתור ורושל בלפר למחקר ביורפואי
    מרצהDr. Myriam Grunewald
    מארגן
    מכון סגול לאריכות ימים
    צרו קשר
    תקצירShow full text abstract about <p>As life expectancy increases, age-related diseases ...»
    <p>As life expectancy increases, age-related diseases are becoming more prevalent. While these conditions are traditionally studied in isolation, mounting evidence points to shared, systemic mechanisms underlying these conditions. Our research highlights the vasculature as &nbsp;a key player in organ homeostasis and repair, and a system shared across all organs—making its dysfunction potential driver of age-related pathologies.</p><p>We demonstrate that manipulating <strong>VEGF signaling</strong> to counteract age-related microvascular rarefaction promotes <strong>comprehensive geroprotection</strong>, preserving organ function and delaying disease onset. Our findings also reveal a link between vascular rarefaction and altered RNA splicing. While hypoxia-driven and age-related changes in alternative RNA splicing have been studied independently, we propose a unifying mechanism that links the two. To explore this further, we also employ patient-derived organoids, which retain their biological age in culture, providing a robust in vitro platform to test anti-aging interventions.</p><p>Our findings support a <strong>vascular theory of aging</strong>, identifying vascular health as a promising target to mitigate age-related diseases and promote healthier aging.</p>
    הרצאה
  • Date:18שלישימרץ 2025

    Proteome-wide prediction of protein-protein interaction networks and protein compound interactions and their integration for biological discovery

    More information
    שעה
    14:00 - 15:00
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהProf. Barry Honig
    מארגן
    המחלקה לביולוגיה מבנית וכימית
    הרצאה
  • Date:20חמישימרץ 2025

    Harnessing Mistakes to Expose Cancer’s Vulnerability

    More information
    שעה
    12:30 - 14:00
    כותרת
    Spotlight on Science lecture sponsored by the Staff Scientists Council
    מיקום
    אולם הרצאות ע"ש גרהרד שמידט
    מרצהIlana Eyal
    Spotlight on Science lecture sponsored by the Staff Scientists Council
    צרו קשר
    תקצירShow full text abstract about <p>Over the past few decades, immunotherapy has revolu...»
    <p>Over the past few decades, immunotherapy has revolutionized cancer treatment with great success in treating cancer patients and preventing tumor recurrence after surgery. Harnessing the immune system to fight cancer largely relies on the ability of T lymphocytes to distinguish&nbsp;between “self” and “non-self” to specifically identify and eliminate malignant cells.&nbsp;This is achieved through the recognition of neoantigens, tumor-specific proteins resulting from genetic mutations.</p><p>The Samuels’ lab is exploring the immune-tumor interactions, with specific focus on the mechanisms underlying cancer-cell recognition, and developing novel strategies to increase antitumor immune responses.</p><p>In this talk, I will present results from our recent studies investigating the link between mRNA mistranslation in cancer cells and immunological tumor control.</p>
    הרצאה
  • Date:20חמישימרץ 2025

    Spatial transcriptomics of pancreatic cancer development and immune cells targeting to restrict tumor growth

    More information
    שעה
    14:00 - 15:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    Auditorium
    מרצהDr. Oren Parnas
    מארגן
    המכון לחקר הטיפול בסרטן עש דואק
    הרצאה
  • Date:24שנימרץ 2025

    Foundations of Computer Science Seminar

    More information
    שעה
    11:15 - 12:15
    כותרת
    Privacy amplification by random allocation (is approximately Poisson subsampling)
    מיקום
    בניין יעקב זיסקינד
    Room 1 - 1 חדר
    מרצהMoshe Shenfeld
    Hebrew University of Jerusalem
    מארגן
    המחלקה למדעי המחשב ומתמטיקה שימושית
    צרו קשר
    תקצירShow full text abstract about Given two distributions P, Q and an integer t, we analyze tw...»
    Given two distributions P, Q and an integer t, we analyze two sampling processes. In "random allocation," we first sample an index i uniformly from [t], then draw r_{i} ~ P and r_{j} ~ Q for all other j in [t]. In "Poisson sampling," we independently draw r_{i} ~ 1/t*P + (1-1/t)*Q for each i in [t]. We bound the difference between these processes' output distributions and the baseline of sampling r_{i} ~ Q for all i.

    This theoretical result provides key insights for analyzing DP-SGD, a privacy-preserving variant of stochastic gradient descent. While Poisson subsampling has well-understood privacy guarantees, common implementations use element shuffling, which was recently shown to have larger privacy losses in certain regimes. Random allocation offers a middle ground, and we prove its privacy analysis reduces to comparing the distributions described above.

    We show that these variants' privacy guarantees are within a constant factor of each other across all parameter regimes and converge asymptotically in t. Our proof has two key components: decomposing Poisson sampling into a mixture of random allocation processes, and showing that random allocation can be viewed as a modified Poisson process where sampling probabilities depend on previous outputs.

    Joint work with Vitaly Feldman
    הרצאה
  • Date:27חמישימרץ 2025

    Regulation of immune cell function in tumor microenvironment of triple-negative breast cancer

    More information
    שעה
    14:00 - 15:00
    מיקום
    בניין ע"ש מקס ולילאן קנדיוטי
    Auditorium
    מרצהProf. Idit Shachar
    מארגן
    המכון לחקר הטיפול בסרטן עש דואק
    הרצאה
  • Date:27חמישימרץ 2025

    To be announced

    More information
    שעה
    15:00 - 16:00
    מיקום
    בניין לביוכימיה על שם נלה וליאון בנוזיו
    Auditorium Rm. 191
    מרצהKeren Yizhak
    (Technion)
    הרצאה

Pages