The Weizmann Institute established a unique In Vivo Imaging Center, which provides Weizmann scientists access to state-of-the art imaging equipment to support wide range of scientific projects for in-vivo imaging in pre-clinical rodents models of human disease (mice and rats). Three of these multiple imaging modalities are based on the basics of magnetic resonance: a 9.4 Tesla Bruker (Germany) Biospec MRI system, a Bruker's Minispec LF50 body composition analyzer and a contrast agent analyzer.
MRI: Magnetic Resonance Imaging is one of the most important imaging modalities in biomedicine. It provides images with high spatial resolution and offers non-invasive direct imaging in any desired spatial plane.
Inbal Biton
You must have an IACUC approved protocol under which these animals will be studied.
Available magnetic resonance imaging (MRI) techniques
- High-resolution imaging
- Relaxivity measurements (T1, T2, PD, T2*)
- Diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI)
- Perfusion MRI
- Cardiac MRI
- Magnetic resonance angiography (MRA)
- Chemical shift imaging (CSI)
- Localized and non-localized spectroscopy
- Pharmacological MRI
- Whole body composition analysis
Scheduling
- The 9.4T MRI scanner is accessible to anyone who has been authorized by Dr. Inbal Biton. Experiments can be scheduled, through Dr. Inbal Biton, at most a month in advance. In general on weekday the scanner is available for use at three shifts, morning (between 8am – 2pm), afternoon (between 2pm -8pm) and night (8pm-8am). On the weekend the scanner is available from 8am until 8pm. Users should send their MRI requests by mail for next month until the 15th of the current month. Cancellation requests must be sent 24 hours before hand, otherwise the users will be charge for the MRI shift.
- Body Composition /contrast agent scanners are accessible to anyone who has been authorized to use the scanners. New users must contact Dr. Inbal Biton for authorization process. All experiments must be scheduled online through > InVivo Imaging Unit. Scheduling is made on a first-come first serve basis but with some flexibility for those investigators with time sensitive experiments.
Bioimaging
More information about in-vivo and in-vitro bio-imaging may be found at Bioimaging@WIS