Research

Retrograde injury signaling in lesioned nerve

This line of research addresses a long-standing problem in the field of nerve regeneration: how does the cell body receive information about an injury from the distant lesion site in the axon.

Cell Length/Size Sensing

In recent years we expanded our focus from questions of how cells transport signals over intracellular distance to the question of how cells can actually sense or measure such distances, or in other words the fundamental cell biological issue of cell size homeostasis

Importin Functions in Physiology and Disease

How does importin-mediated transport and importin-dependent signaling impact physiology, behavior, and pathology? Is long-distance transport of importin cargos necessary for neuronal functions or maintenance? Can modulation of importin-mediated transport be targeted to address human diseases?