Metabolic Profiling Publications

  1. Yossef Y. T. A., Peremen L. S., Telerman A., Goldinger G., Malitsky S., Itkin M., Halperin R., Yaloz N. P. & Tirosh A. (2025). Single-cell transcriptomics and metabolomic analysis reveal adenosine-derived metabolites over-representation in pseudohypoxic neuroendocrine tumours.  Clinical and Translational Medicine. 2025 Feb , 15 (2).
  2. Yirmiya E., Hobbs S. J., Leavitt A., Osterman I., Avraham C., Hochhauser D., Madhala B., Skovorodka M., Tan J. M., Toyoda H. C., Chebotar I., Itkin M., Malitsky S., Amitai G., Kranzusch P. J. & Sorek R. (2025). Structure-guided discovery of viral proteins that inhibit host immunity.  Cell. 2025 Jan 23 , .
  3. Yirmiya E., Hobbs S. J., Leavitt A., Osterman I., Avraham C., Hochhauser D., Madhala B., Skovorodka M., Tan J. M., Toyoda H. C., Chebotar I., Itkin M., Malitsky S., Amitai G., Kranzusch P. J. & Sorek R. (2025). Structure-guided discovery of viral proteins that inhibit host immunity.  Cell. 2025 Jan 23 , .
  4. Chourasia S., Petucci C., Shoffler C., Abbasian D., Wang H., Han X., Sivan E., Brandis A., Mehlman T., Malitsky S., Itkin M., Sharp A., Rotkopf R., Dassa B., Regev L., Zaltsman Y. & Gross A. (2025). MTCH2 controls energy demand and expenditure to fuel anabolism during adipogenesis.  EMBO Journal. 2025 Jan 3 , .
  5. Rousset F., Osterman I., Scherf T., Falkovich A. H., Leavitt A., Amitai G., Shir S., Malitsky S., Itkin M., Savidor A. & Sorek R. (2025). TIR signaling activates caspase-like immunity in bacteria.  Science (New York, N.Y.). 2025 Jan 31 , 387 (6733):510-516.
  6. Chourasia S., Petucci C., Shoffler C., Abbasian D., Wang H., Han X., Sivan E., Brandis A., Mehlman T., Malitsky S., Itkin M., Sharp A., Rotkopf R., Dassa B., Regev L., Zaltsman Y. & Gross A. (2025). MTCH2 controls energy demand and expenditure to fuel anabolism during adipogenesis.  EMBO Journal. 2025 Jan 3 , .
  7. Rousset F., Osterman I., Scherf T., Falkovich A. H., Leavitt A., Amitai G., Shir S., Malitsky S., Itkin M., Savidor A. & Sorek R. (2025). TIR signaling activates caspase-like immunity in bacteria.  Science (New York, N.Y.). 2025 Jan 31 , 387 (6733):510-516.
  8. Cohen-Hoch D., Chen T., Sharabi L., Dezorella N., Itkin M., Feiguelman G., Malitsky S. & Fluhr R. (2025). Osmotic stress in roots drives lipoxygenase-dependent plastid remodeling through singlet oxygen production.  Plant Physiology. 2025 Jan , 197 (1).
  9. Cohen-Hoch D., Chen T., Sharabi L., Dezorella N., Itkin M., Feiguelman G., Malitsky S. & Fluhr R. (2025). Osmotic stress in roots drives lipoxygenase-dependent plastid remodeling through singlet oxygen production.  Plant Physiology. 2025 Jan , 197 (1).
  10. Yossef Y. T. A., Peremen L. S., Telerman A., Goldinger G., Malitsky S., Itkin M., Halperin R., Yaloz N. P. & Tirosh A. (2025). Single-cell transcriptomics and metabolomic analysis reveal adenosine-derived metabolites over-representation in pseudohypoxic neuroendocrine tumours.  Clinical and Translational Medicine. 2025 Feb , 15 (2).
  11. Eliason O., Malitsky S., Panizel I., Feldmesser E., Porat Z., Sperfeld M. & Segev E. (2024). The photo-protective role of vitamin D in the microalga Emiliania huxleyi.  iScience. 2024 Jun 21 , 27 (6).
  12. Osterman I., Samra H., Rousset F., Loseva E., Itkin M., Malitsky S., Yirmiya E., Millman A. & Sorek R. (2024). Phages reconstitute NAD+ to counter bacterial immunity.  Nature. 2024 Oct 31 , 634 (8036):1160-1167.
  13. Lim L. Q. J., Adler L., Hajaj E., Soria L. R., Perry R. B. T., Darzi N., Brody R., Furth N., Lichtenstein M., Bab-Dinitz E., Porat Z., Melman T., Brandis A., Aylon Y., Ben-Dor S., Orr I., Pri-Or A., Seger R., Shaul Y., Ruppin E., Oren M., Perez M., Meier J., Brunetti-Pierri N., Shema E., Ulitsky I., Erez A., Malitsky S. & Itkin M. (2024). ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.  Nature metabolism. 2024 Jul , 6 (7):1294-1309.
  14. Osterman I., Samra H., Rousset F., Loseva E., Itkin M., Malitsky S., Yirmiya E., Millman A. & Sorek R. (2024). Phages reconstitute NAD+ to counter bacterial immunity.  Nature. 2024 Oct 31 , 634 (8036):1160-1167.
  15. Vinik Y., Maimon A., Dubey V., Raj H., Abramovitch I., Malitsky S., Itkin M., Ma'ayan A., Westermann F., Gottlieb E., Ruppin E. & Lev S. (2024). Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy.  Advanced Science. 2024 Mar 5 , 11 (17).
  16. Lim L. Q. J., Adler L., Hajaj E., Soria L. R., Perry R. B. T., Darzi N., Brody R., Furth N., Lichtenstein M., Bab-Dinitz E., Porat Z., Melman T., Brandis A., Aylon Y., Ben-Dor S., Orr I., Pri-Or A., Seger R., Shaul Y., Ruppin E., Oren M., Perez M., Meier J., Brunetti-Pierri N., Shema E., Ulitsky I., Erez A., Malitsky S. & Itkin M. (2024). ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.  Nature metabolism. 2024 Jul , 6 (7):1294-1309.
  17. Vinik Y., Maimon A., Dubey V., Raj H., Abramovitch I., Malitsky S., Itkin M., Ma'ayan A., Westermann F., Gottlieb E., Ruppin E. & Lev S. (2024). Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy.  Advanced Science. 2024 Mar 5 , 11 (17).
  18. Sperfeld M., Narváez-Barragán D. A., Malitsky S., Frydman V., Yuda L., Rocha J. & Segev E. (2024). Algal methylated compounds shorten the lag phase of Phaeobacter inhibens bacteria.  Nature Microbiology. 2024 Aug , 9 (8):2006-2021.
  19. Dong Y. & Malitsky S. (2024). MetaboReport: from metabolomics data analysis to comprehensive reporting.  Bioinformatics. 2024 Jun 1 , 40 (6).
  20. Eliason O., Malitsky S., Panizel I., Feldmesser E., Porat Z., Sperfeld M. & Segev E. (2024). The photo-protective role of vitamin D in the microalga Emiliania huxleyi.  iScience. 2024 Jun 21 , 27 (6).