Targeted Metabolomics Publications

  1. Moraïs S., Mazor M., Tovar-Herrera O., Zehavi T., Zorea A., Ifrach M., Bogumil D., Brandis A., Walter J., Elia N., Gur E. & Mizrahi I. (2024). Plasmid-encoded toxin defence mediates mutualistic microbial interactions.  Nature Microbiology. 2024 Jan , 9 :108-119.
  2. Lim L. Q. J., Adler L., Hajaj E., Soria L. R., Perry R. B. T., Darzi N., Brody R., Furth N., Lichtenstein M., Bab-Dinitz E., Porat Z., Melman T., Brandis A., Aylon Y., Ben-Dor S., Orr I., Pri-Or A., Seger R., Shaul Y., Ruppin E., Oren M., Perez M., Meier J., Brunetti-Pierri N., Shema E., Ulitsky I., Erez A., Malitsky S. & Itkin M. (2024). ASS1 metabolically contributes to the nuclear and cytosolic p53-mediated DNA damage response.  Nature metabolism. 2024 Jul , 6 (7):1294-1309.
  3. Stroganov S., Harris T., Alyagor L., Ben Moyal L., Plitman Mayo R., Golani O., Hirsch D., Ben-Dor S., Brandis A., Mehlman T., Kovo M., Biron-Shental T., Dekel N. & Neeman M. (2024). The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta.  eLife. 2024 Feb 5 , 13 .
  4. Bahat A., Itzhaki E., Weiss B., Tolmasov M., Tsoory M., Kuperman Y., Brandis A., Shurrush K. A. & Dikstein R. (2024). Lowering mutant huntingtin by small molecules relieves Huntingtons disease symptoms and progression.  EMBO Molecular Medicine. 2024 Feb 19 , 16 (3):523-546.
  5. Garb J., Amitai G., Lu A., Ofir G., Brandis A., Mehlman T., Kranzusch P. J. & Sorek R. (2024). The SARM1 TIR domain produces glycocyclic ADPR molecules as minor products.  PLoS ONE. 2024 Apr 18 , 19 (4 ).
  6. Schlichter Kadosh Y., Muthuraman S., Nisaa K., Ben-Zvi A., Karsagi Byron D. L., Shagan M., Brandis A., Mehlman T., Gopas J., Saravana Kumar R. & Kushmaro A. (2024). Pseudomonas aeruginosa quorum sensing and biofilm attenuation by a di-hydroxy derivative of piperlongumine (PL-18).  Biofilm. 2024 Dec , 8 .
  7. Goldsmith M., Avram L., Brandis A., Mehlman T., Ben-Dor S., Peleg Y., Ben-Zeev E., Barbole R. S. & Reich Z. (2024). LsBOS utilizes oxalyl-CoA produced by LsAAE3 to synthesize β-ODAP in grass pea.  Nature Communications. 2024 Aug 8 , 15 .
  8. Brandis A., Roy D., Das I., Sheves M. & Eisenbach M. (2024). Uncommon opsins retinal isomer is involved in mammalian sperm thermotaxis.  Scientific Reports. 2024 May 10 , 14 .
  9. Duncan-Lowey B., Tal N., Johnson A. G., Rawson S., Mayer M. L., Doron S., Millman A., Melamed S., Fedorenko T., Kacen A., Brandis A., Mehlman T., Amitai G., Sorek R. & Kranzusch P. J. (2023). Cryo-EM structure of the RADAR supramolecular anti-phage defense complex.  Cell. 2023 Mar 2 , 186 (5):987-998.
  10. Chourasia S., Petucci C., Wang H., Han X., Sivan E., Brandis A., Mehlman T., Malitsky S., Itkin M., Rotkopf R., Regev L., Zaltsman Y. & Gross A. (2023). High-energy demand and nutrient exhaustion in MTCH2 knockout cells.  BioRxiv. 2023 Dec 16 , .
  11. Uzonyi A., Dierks D., Nir R., Kwon O. S., Toth U., Barbosa I., Burel C., Brandis A., Rossmanith W., Le Hir H., Slobodin B. & Schwartz S. (2023). Exclusion of m6A from splice-site proximal regions by the exon junction complex dictates m6A topologies and mRNA stability.  Molecular Cell. 2023 Jan 19 , 83 (2):237-251.e7.
  12. Koh E., Chaturvedi A. K., Javitt G., Brandis A. & Fluhr R. (2023). Multiple paths of plant host toxicity are associated with the fungal toxin cercosporin.  Plant Cell And Environment. 2023 Aug , 46 (8):2542-2557.
  13. Barak-Gavish N., Dassa B., Kuhlisch C., Nussbaum I., Brandis A., Rosenberg G., Avraham R. & Vardi A. (2023). Bacterial lifestyle switch in response to algal metabolites.  eLife. 2023 Jan 24 , 12 .
  14. Rousset F., Yirmiya E., Nesher S., Brandis A., Mehlman T., Itkin M., Malitsky S., Millman A., Melamed S. & Sorek R. (2023). A conserved family of immune effectors cleaves cellular ATP upon viral infection.  Cell. 2023 Aug 17 , 186 (17):3619-3631.e13.
  15. Suzzi S., Croese T., Ravid A., Gold O., Clark A. R., Medina S., Kitsberg D., Adam M., Vernon K. A., Kohnert E., Shapira I., Malitsky S., Itkin M., Brandis A., Mehlman T., Salame T. M., Colaiuta S. P., Cahalon L., Slyper M., Greka A., Habib N. & Schwartz M. (2023). N-acetylneuraminic acid links immune exhaustion and accelerated memory deficit in diet-induced obese Alzheimers disease mouse model.  Nature Communications. 2023 Dec , 14 (1).
  16. Nobs S. P., Kolodziejczyk A. A., Adler L., Horesh N., Botscharnikow C., Herzog E., Mohapatra G., Hejndorf S., Hodgetts R. J., Spivak I., Schorr L., Fluhr L., Kviatcovsky D., Zacharia A., Njuki S., Barasch D., Stettner N., Dori-Bachash M., Harmelin A., Brandis A., Mehlman T., Erez A., He Y., Ferrini S., Puschhof J., Shapiro H., Kopf M., Moussaieff A., Abdeen S. K. & Elinav E. (2023). Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes.  Nature. 2023 Dec 21 , 624 (7992):645-652.
  17. Ben Ami S. D., Ehre D., Ushakov A., Mehlman T., Brandis A., Alikin D., Shur V., Kholkin A., Lahav M. & Lubomirsky I. (2022). Engineering of Pyroelectric Crystals Decoupled from Piezoelectricity as Illustrated by Doped α-Glycine.  Angewandte Chemie - International Edition. 2022 Dec 5 , 61 (49).
  18. Koh E., Brandis A. & Fluhr R. (2022). Plastid and cytoplasmic origins of 1O2-mediated transcriptomic responses.  Frontiers in Plant Science. 2022 Nov 7 , 13 .
  19. Serger E., Luengo-Gutierrez L., Chadwick J. S., Kong G., Zhou L., Crawford G., Danzi M. C., Myridakis A., Brandis A., Bello A. T., Müller F., Sanchez-Vassopoulos A., De Virgiliis F., Liddell P., Dumas M. E., Strid J., Mani S., Dodd D. & Di Giovanni S. (2022). The gut metabolite indole-3 propionate promotes nerve regeneration and repair.  Nature (London). 2022 Jul 21 , 607 (7919):585-592.
  20. Goldsmith M., Barad S., Knafo M., Savidor A., Ben-Dor S., Brandis A., Mehlman T., Peleg Y., Albeck S., Dym O., Ben-Zeev E., Barbole R. S., Aharoni A. & Reich Z. (2022). Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.  The journal of Biological chemistry. 2022 May 1 , 298 (5).