Metabolic Profiling Publications

  1. Kugler A., Kumari P., Kokabi K., Itkin M., Malitsky S. & Khozin-Goldberg I. (2020). Resilience to Freezing in the Vegetative Cells of the Microalga Lobosphaera incisa (Trebouxiophyceae, Chlorophyta).  Journal of Phycology. 2020 Apr , 56 (2):334-345.
  2. Rabinovich S., Silberman A., Adler L., Agron S., Levin-Zaidman S., Bahat A., Porat Z., Ben-Zeev E., Geva I., Itkin M., Malitsky S., Buchaklian A., Helbling D., Dimmock D. & Erez A. (2020). The mitochondrial carrier Citrin plays a role in regulating cellular energy during carcinogenesis.  Oncogene. 2020 Jan 2 , 39 (1):164-175.
  3. Keshet R., Lee J. S., Adler L., Iraqi M., Ariav Y., Lim L. Q. J., Lerner S., Rabinovich S., Oren R., Katzir R., Tishler H. W., Stettner N., Goldman O., Landesman H., Galai S., Kuperman Y., Kuznetsov Y., Brandis A., Mehlman T., Malitsky S., Itkin M., Koehler S. E., Zhao Y., Talsania K., Shen T., Peled N., Ulitsky I., Porgador A., Ruppin E. & Erez A. (2020). Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors.  Nature Cancer. 2020 Sept , 1 (9):894-908.
  4. Kokabi K., Gorelova O., Zorin B., Didi-Cohen S., Itkin M., Malitsky S., Solovchenko A., Boussiba S. & Khozin-Goldberg I. (2020). Lipidome Remodeling and Autophagic Respose in the Arachidonic-Acid-Rich Microalga Lobosphaera incisa Under Nitrogen and Phosphorous Deprivation.  Frontiers in Plant Science. 2020 Nov 27 , 11 .
  5. Gabay G., Faigenboim A., Dahan Y., Izhaki Y., Itkin M., Malitsky S., Elkind Y. & Flaishman M. A. (2019). Transcriptome analysis and metabolic profiling reveal the key role of α-linolenic acid in dormancy regulation of European pear.  Journal of Experimental Botany. 2019 Jan 30 , 70 (3):1017-1031.
  6. Kokabi K., Gorelova O., Ismagulova T., Itkin M., Malitsky S., Boussiba S., Soloychenko A. & Khozin-Goldberg I. (2019). Metabolomic foundation for differential responses of lipid metabolism to nitrogen and phosphorus deprivation in an arachidonic acid-producing green microalga.  Plant Science. 2019 Jun , 283 :95-115.
  7. Ganin H., Kemper N., Meir S., Rogachev I., Ely S., Massalha H., Mandabi A., Keren-Paz A., Shanzer A., Meijler M., Malitsky S., Aharoni A. & Kolodkin-Gal I. (2019). Indole derivatives maintain the status quo between beneficial biofilms and their plant hosts.  Molecular Plant-Microbe Interactions. 2019 Aug , 32 (8):1013-1025.
  8. Barak-Gavish N., Frada M. J., Ku C., Lee P. A., DiTullio G. R., Malitsky S., Aharoni A., Green S. J., Rotkopf R., Kartvelishvily E., Sheyn U., Schatz D. & Vardi A. (2018). Bacterial virulence against an oceanic bloom-forming phytoplankter is mediated by algal DMSP.  Science Advances. 2018 Oct 24 , 4 (10).
  9. Polturak G., Heinig U., Grossman N., Battat M., Leshkowitz D., Malitsky S., Rogachev I. & Aharoni A. (2018). Transcriptome and Metabolic Profiling Provides Insights into Betalain Biosynthesis and Evolution in Mirabilis jalapa.  Molecular Plant. 2018 Jan 8 , 11 (1):189-204.
  10. Sonawane P. D., Heinig U., Panda S., Gilboa N. S., Yona M., Kumar S. P., Alkan N., Unger T., Bocobza S., Pliner M., Malitsky S., Tkachev M., Meir S., Rogachev I. & Aharoni A. (2018). Short-chain dehydrogenase/reductase governs steroidal specialized metabolites structural diversity and toxicity in the genus Solanum.  Proceedings of the National Academy of Sciences of the United States of America. 2018 Jun 5 , 115 (23):E5419-E5428.
  11. Lee J. S., Adler L., Karathia H., Carmel N., Rabinovich S., Auslander N., Keshet R., Stettner N., Silberman A., Agemy L., Helbling D., Eilam R., Sun Q., Brandis A., Malitsky S., Itkin M., Weiss H., Pinto S., Kalaora S., Levy R., Barnea E., Admon A., Dimmock D., Stern-Ginossar N., Scherz A., Nagamani S. C. S., Unda M., Wilson D. M., Elhasid R., Carracedo A., Samuels Y., Hannenhalli S., Ruppin E. & Erez A. (2018). Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures.  Cell. 2018 Sept 6 , 174 (6):1559-1570.
  12. Sonawane P. D., Pollier J., Panda S., Szymanski J., Massalha H., Yona M., Unger T., Malitsky S., Arendt P., Pauwels L., Almekias-Siegl E., Rogachev I., Meir S., Cardenas P. D., Masri A., Petrikov M., Schaller H., Schaffer A. A., Kamble A., Giri A. P., Goossens A. & Aharoni A. (2017). Plant cholesterol biosynthetic pathway overlaps with phytosterol metabolism.  Nature Plants. 2017 Jan , 3 .
  13. Schatz D., Rosenwasser S., Malitsky S., Wolf S. G., Feldmesser E. & Vardi A. (2017). Communication via extracellular vesicles enhances viral infection of a cosmopolitan alga.  Nature Microbiology. 2017 Nov , 2 (11):1485-1492.
  14. Paudel J. R., Davidson C., Song J., Maxim I., Aharoni A. & Tai H. H. (2017). Pathogen and pest responses are altered due to RNAi-mediated knockdown of GLYCOALKALOID METABOLISM 4 in solanum tuberosum.  Molecular Plant-Microbe Interactions. 2017 Nov , 30 (11):876-885.
  15. Cohen H., Hacham Y., Panizel I., Rogachev I., Aharoni A. & Amir R. (2017). Repression of CYSTATHIONINE γ-SYNTHASE in seeds recruits the S-methylmethionine cycle.  Plant Physiology. 2017 Jul , 174 :1322-1333.