Targeted Metabolomics Publications

  1. Serger E., Luengo-Gutierrez L., Chadwick J. S., Kong G., Zhou L., Crawford G., Danzi M. C., Myridakis A., Brandis A., Bello A. T., Müller F., Sanchez-Vassopoulos A., De Virgiliis F., Liddell P., Dumas M. E., Strid J., Mani S., Dodd D. & Di Giovanni S. (2022). The gut metabolite indole-3 propionate promotes nerve regeneration and repair.  Nature (London). 2022 Jul 21 , 607 (7919):585-592.
  2. Goldsmith M., Barad S., Knafo M., Savidor A., Ben-Dor S., Brandis A., Mehlman T., Peleg Y., Albeck S., Dym O., Ben-Zeev E., Barbole R. S., Aharoni A. & Reich Z. (2022). Identification and characterization of the key enzyme in the biosynthesis of the neurotoxin β-ODAP in grass pea.  The journal of Biological chemistry. 2022 May 1 , 298 (5).
  3. Noronha A., Belugali Nataraj N., Sang Lee J., Zhitomirsky B., Oren Y., Oster S., Lindzen M., Mukherjee S., Will R., Ghosh S., Simoni-Nieves A., Verma A., Chatterjee R., Borgoni S., Robinson W., Sinha S., Brandis A., Kerr D. L., Wu W., Sekar A., Giri S., Chung Y., Drago-Garcia D., Danysh B. P., Lauriola M., Fiorentino M., Ardizzoni A., Oren M., Blakely C. M., Ezike J., Wiemann S., Parida L., Bivona T. G., Aqeilan R. I., Brugge J. S., Regev A., Getz G., Ruppin E. & Yarden Y. (2022). AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer.  Cancer Discovery. 2022 Nov 1 , 12 (11):2666-2683.
  4. Goldsmith M., Barad S., Peleg Y., Albeck S., Dym O., Brandis A., Mehlman T. & Reich Z. (2022). The identification and characterization of an oxalyl-CoA synthetase from grass pea ( Lathyrus sativus L.).  RSC Chemical Biology. 2022 Mar 9 , 3 (3):320-333.
  5. Millman A., Melamed S., Leavitt A., Doron S., Bernheim A., Hör J., Garb J., Bechon N., Brandis A., Lopatina A., Ofir G., Hochhauser D., Stokar-Avihail A., Tal N., Sharir S., Voichek M., Erez Z., Ferrer J. L. M., Dar D., Kacen A., Amitai G. & Sorek R. (2022). An expanded arsenal of immune systems that protect bacteria from phages.  Cell Host and Microbe. 2022 Nov 9 , 30 (11):1556-1569e5.
  6. Brekelmans J., Dickman M. M., Verma S., Arba-Mosquera S., Goldschmidt R., Goz A., Brandis A., Berendschot T. T., Saelens I. E., Marcovich A. L., Scherz A. & Nuijts R. M. (2022). Excimer laser-assisted corneal epithelial pattern ablation for corneal cross-linking.  Acta Ophthalmologica. 2022 Jun , 100 (4):422-430.
  7. Allouche-Arnon H., Khersonsky O., Tirukoti N. D., Peleg Y., Dym O., Albeck S., Brandis A., Mehlman T., Avram L., Harris T., Yadav N. N., Fleishman S. J. & Bar-Shir A. (2022). Computationally designed dual-color MRI reporters for noninvasive imaging of transgene expression.  Nature biotechnology. 2022 Jul , 40 (7):1143-1149.
  8. Fortus D., Ofek-Geva E., Vinker-Shuster M., Mehlman T., Malitsky S., Brandis A. & Yeshayahu Y. (2021). The Onset of Puberty and Adolescents Motivation to Learn Science.  Adolescent Health. 2021, .
  9. Fluhr L., Mor U., Kolodziejczyk A. A., Dori-Bachash M., Leshem A., Itav S., Cohen Y., Suez J., Zmora N., Moresi C., Ayalon N., Valdés-Mas R., Molina S., Hornstein S., Karbi H., Kviatcovsky D., Livne A., Bukimer A., Eliyahu-Miller S., Metz A., Brandis A., Mehlman T., Kuperman Y., Tsoory M., Stettner N., Harmelin A., Shapiro H. & Elinav E. (2021). Gut microbiota modulates weight gain in mice after discontinued smoke exposure.  Nature (London). 2021 Dec 23 , 600 (7890):713-719.
  10. Bartok O., Pataskar A., Nagel R., Laos M., Goldfarb E., Hayoun D., Levy R., Körner P., Kreuger I. Z. M., Champagne J., Zaal E. A., Bleijerveld O. B., Huang X., Kenski J., Wargo J., Brandis A., Levin Y., Mizrahi O., Alon M., Lebon S., Yang W., Nielsen M. M., Stern-Ginossar N., Altelaar M., Berkers C. R., Geiger T., Peeper D. S., Olweus J., Samuels Y. & Agami R. (2021). Anti-tumour immunity induces aberrant peptide presentation in melanoma.  Nature. 2021 Feb 11 , 590 (7845):332-337.
  11. Dierks D., Garcia-Campos M. A., Uzonyi A., Safra M., Edelheit S., Rossi A., Sideri T., Varier R. A., Brandis A., Stelzer Y., van Werven F., Scherz-Shouval R. & Schwartz S. (2021). Multiplexed profiling facilitates robust m6A quantification at site, gene and sample resolution.  Nature Methods. 2021 Sept 3 , 18 (9):1060-1067.
  12. Tal N., Morehouse B. R., Millman A., Stokar-Avihail A., Avraham C., Fedorenko T., Yirmiya E., Herbst E., Brandis A., Mehlman T., Oppenheimer-Shaanan Y., Keszei A. F., Shao S., Amitai G., Kranzusch P. J. & Sorek R. (2021). Cyclic CMP and cyclic UMP mediate bacterial immunity against phages.  Cell. 2021 Nov 11 , 184 (23):5728-5739.e16.
  13. Even A., Morelli G., Turchetto S., Shilian M., Bail R. L., Laguesse S., Krusy N., Brisker A., Brandis A., Inbar S., Chariot A., Saudou F., Dietrich P., Dragatsis I., Brone B., Broix L., Rigo J., Weil M. & Nguyen L. (2021). ATP-citrate lyase promotes axonal transport across species.  Nature Communications. 2021 Oct 7 , 12 (1).
  14. Koh E., Cohen D., Brandis A. & Fluhr R. (2021). Attenuation of cytosolic translation by RNA oxidation is involved in singlet oxygen-mediated transcriptomic responses.  Plant, Cell and Environment. 2021 Nov , 44 (11):3597-3615.
  15. Panayotis N., Freund P. A., Marvaldi L., Shalit T., Brandis A., Mehlman T., Tsoory M. M. & Fainzilber M. (2021). β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice.  Cell Reports Medicine. 2021 May 18 , 2 (5).
  16. Gnainsky Y., Zfanya N., Elgart M., Omri E., Brandis A., Mehlman T., Itkin M., Malitsky S., Adamski J. & Soen Y. (2021). Systemic Regulation of Host Energy and Oogenesis by Microbiome-Derived Mitochondrial Coenzymes.  Cell Reports. 2021 Jan 5 , 34 (1).
  17. Lerner S., Eilam R., Adler L., Tsoory M., Brandis A. & Erez A. (2021). ASL expression in ALDH1A1 + neurons in the substantia nigra metabolically contributes to neurodegenerative phenotype.  Human Genetics. 2021 Oct , 140 (10):1471-1485.
  18. Gabizon R., Shraga A., Gehrtz P., Livnah E., Shorer Y., Gurwicz N., Avram L., Unger T., Aharoni H., Albeck S., Brandis A., Shulman Z., Katz B., Herishanu Y. & London N. (2020). Efficient targeted degradation via reversible and irreversible covalent PROTACs.  Journal of the American Chemical Society. 2020 Jul 8 , 142 (27):11734-11742.
  19. Marcovich A. L., Brekelmans J., Brandis A., Samish I., Pinkas I., Preise D., Sasson K., Feine I., Goz A., Dickman M. M., Nuijts R. M. & Scherz A. (2020). Decreased riboflavin impregnation time does not increase the risk for endothelial phototoxicity during corneal cross-linking.  Translational Vision Science and Technology. 2020 May , 9 (6).
  20. Brekelmans J., Veugen J., Rieff K., Dickman M. M., Goz A., Wolffs P., Brandis A., Berendschot T. T., Nuijts R. M., Scherz A. & Marcovich A. L. (2020). Enzymatic digestion of porcine corneas cross-linked by hypo-and hyperosmolar formulations of riboflavin/ultraviolet A or WST11/near-infrared light.  Translational Vision Science and Technology. 2020 Sept 3 , 9 (10):1-9.