Serotonin & psychedelics

 

Animals adapt their behaviors according to their past experiences and changes in the surrounding environment. This adaptation could be useful but also harmful. We investigate the behavioral roles and computational principles of how the serotonin system in the brain controls adaptive and maladaptive behaviors.

We recently extended our approach to the study of psychedelics and anxiety-related behaviors, which stimulate serotonin pathways in the brain.

 

Related literature:

[1] Braun*, Rosenberg* et al.,
    "High-resolution tracking of unconfined zebrafish behavior reveals stimulatory and anxiolytic effects of psilocybin"
    Molecular Psychiatry. (2024)

[2] Kawashima
    "The role of the serotonergic system in motor control"
    Neuroscience Research. 129: 32-39 (2019)

[3] Kawashima et al.
   "The Serotonergic System Tracks the Outcomes of Actions to Mediate Short-Term Motor Learning"
   Cell. 167:933-946 (2016)