Selected Publications

2024

2024

Structural features within the NORAD long noncoding RNA underlie efficient repression of Pumilio activity

S. Farberov, O. Ziv, J.Y. Lau, R. Ben-Tov Perry, Y. Lubelsky, E. Miska, G. Kudla and I. Ulitsky. Structural features within the NORAD long noncoding RNA underlie efficient repression of Pumilio activity. Nature Structural and Molecular Biology (2024)

9

2023

2023

Silc1 long noncoding RNA is an immediate-early gene promoting efficient memory formation

R. Ben-Tov Perry, M. Tsoory, M. Tolmasov and I. Ulitsky. Cell Reports 42(10):113168 (2023)

2023

Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus

N. Gil, R. Ben-Tov Perry, A. Tuck, M. Buhler and I. Ulitsky. Cell Reports. 42(6):112569 (2023)

2023

Massively parallel identification of mRNA localization elements in primary cortical neurons

S. Mendonsa*, N. von Kügelgen*, S. Dantsuji*, M. Ron*, L. Breimann, A. Baranovskii, I. Lödige, M. Kirchner, M. Fischer, N. Zerna, L. Bujanic, P. Mertins, I. Ulitsky^# and M Chekulaeva^#. Nature Neuroscience. 26(3):394-405 (2023) (* - equal contribution, # - co-corresponding authors)

2022

2022

Substoichiometric action of long noncoding RNAs

J.P. Unfried and I. Ulitsky, May 2022, Nature Cell Biology. 5, 24, p. 608-615

2022

Context-specific effects of sequence elements on subcellular localization of linear and circular RNAs

M. Ron and I. Ulitsky, May 2022, Nature Communications. 1, 13, p. 2481

2022

Unique features of transcription termination and initiation at closely spaced tandem human genes

N. Nissani and I. Ulitsky, Apr 2022, Molecular Systems Biology. 4, 18, p. e10682

2021

2021

Highly conserved and cis-acting lncRNAs produced from paralogous regions in the center of HOXA and HOXB clusters in the endoderm lineage

N. Degani, Y. Lubelsky, R. Ben-Tov Perry, E. Ainbinder and I. Ulitsky, Jul 2021, PLoS Genetics. 17, 7, p. e1009681

2021

The sequence-binding-function axes of an RNA nuclear enrichment element

Y. Lubelsky, B. Zuckerman and I. Ulitsky, May 2021, The EMBO Journal. 40:e106357

2020

2020

Uncovering deeply conserved motif combinations in rapidly evolving noncoding sequences

C.J. Ross, A. Rom, A. Spinrad, D. Gelbard Solodkin, N. Degani and I. Ulitsky, Dec 2020, Genome Biology. 1, 22, p. 29

2020

Regulation of neuronal commitment in mouse embryonic stem cells by the Reno1/Bahcc1 locus

H. Hezroni, R. Ben-Tov Perry, N. Gil, N. Degani and I. Ulitsky, Sep 2020, EMBO Reports. 11, 21, p. e51264,

2020

Gene architecture and sequence composition underpin selective dependency of long RNAs on components of the nuclear export pathway

B. Zuckerman, M. Ron, M. Mikl, E. Segal and I. Ulitsky, Jun 2020, Molecular Cell. 79, 2, p. 251-267.e6

2020

Regulation of gene expression by cis-acting long noncoding RNAs

N. Gil and I. Ulitsky, Feb 2020, Nature Reviews Genetics. 21, 2, p. 102-117

2019

2019

Regulation of CHD2 expression by the Chaserr long noncoding RNA is essential for viability

A. Rom, L. Melamed, N. Gil, M. Goldrich, R. Kadir, M. Golan, I. Biton, R. Ben-Tov Perry and I. Ulitsky. , Nov 2019, Nature Communications. 10, 1, p. 5092

2019

Predictive models of subcellular localization of long RNAs

B. Zuckerman and I. Ulitsky, Feb 2019, RNA. 25, 5, p. 557-572

2018

2018

Regulation of Neuroregeneration by Long Noncoding RNAs

R. Ben-Tov Perry, H. Hezroni, M.J. Goldrich and I. Ulitsky, Oct 2018, Molecular Cell. 72, 3, p. 553-567.E5

2018

Production of spliced long noncoding RNAs specifies regions with increased enhancer activity

N. Gil and I. Ulitsky, Jun 2018, Cell Systems. 7, 5, p. 537-547

2018

Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells

Y. Lubelsky and I. Ulitsky, Mar 2018, Nature. 555, 7694, p. 107-111

2018

SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA

A. Tichon, R. Ben-Tov Perry, L. Stojic and I. Ulitsky, Jan 2018, Genes & Development. 32, 1, p. 70-78

2017

2017

A subset of conserved mammalian long non-coding RNAs are fossils of ancestral protein-coding genes

H. Hezroni, R. Ben-Tov Perry, Z. Meir, G. Housman, Y. Lubelsky and I. Ulitsky, I, Feb 2017, Genome Biology. 18, p. 162

2016

2016

A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells

A. Tichon, N. Gil, Y. Lubelsky, T. Havkin Solomon, D. Lemze, S. Itzkovitz, N. Stern-Ginossar and I. Ulitsky, Feb 2016, Nature communications. 7

2016

Evolution to the rescue: using comparative genomics to understand long non-coding RNAs

Ulitsky, I, Feb 2016, Nature Reviews Genetics. 17, p. 601-614

2015

2015

Principles of Long Noncoding RNA Evolution Derived from Direct Comparison of Transcriptomes in 17 Species

H. Hezroni, D. Koppstein, M.G. Schwartz, A. Avrutin, D.P. Bartel and I. Ulitsky, Feb 2015, Cell Reports. 11, p. 1110-1122

2013

2013

lincRNAs: Genomics, Evolution, and Mechanisms

I. Ulitsky and D.P. Bartel, Feb 2013, Cell. 154, p. 26-46

2012

2012

Extensive alternative polyadenylation during zebrafish development

I. Ulitsky, A. Shkumatava, C. Jan, A.O. Subtelny, D. Koppstein, H. Sive and D.P. Bartel, Feb 2012, Genome Research. 22, p. 2054-2066

2011

2011

Conserved Function of lincRNAs in Vertebrate Embryonic Development despite Rapid Sequence Evolution

I. Ulitsky*, A. Shkumatava*, C. Jan, H. Sive and D.P. Bartel, DP, Feb 2011, Cell. 147, p. 1537-1550