The role of mitochondria in health and disease

Biological circuits: design, function and evolution • Regulatory genome: transcription, replication and the chromatin as a communication platform • Developmental patterning: morphogen gradients, scaling, robustness

We study the molecular foundations and applied potential of mammalian pluripotent stem cells in early organ development, germ cell formation and whole synthetic embryo generation ex utero

Drug resistance in cancer, effects that intra-tumor bacteria on cancer biology and drug resistance, ex vivo organ culture for the prediction of drug response

We study morphogenesis, cell biology and function of hypothalamic neurons, which regulate appetite, stress and social behavior

Understanding epithelial, stem and immune cell interactions in the gut

Biophysics, soft matter, active matter

We seek a molecular understanding of membrane remodeling and its contribution to health and disease

Serotonergic control of learning, Development of learning abilities

Studying cell-cell communication mechanisms of malaria parasites within a population and with their hosts

We use molecular genetics and advanced electron microscopy to study pigment cells and the formation of functional and pathological bio-organic crystals.

Proprioception and the the musculoskeletal system in development and disease

Prefrontal cortical circuits, social behavior, learning, decision making, optogenetic tool development

We study interactions between peripheral circadian clocks and exercise physiology, hypoxia signaling and metabolic pathways

Multi modal molecular imaging of regulatory checkpoints in vascular remodeling in reproduction

Studying cellular correlates of tactile perception of rodents

Our studies proceed along three major lines: (1) Microbial population dynamics under stress, (2) Understanding drought resistance and engineering drought-resistant nutritious plants (3) The plant microbiome and its dynamics

We study how antibodies are generated in response to invading pathogens in mouse models, infected subjects and cancer patients. We use this information to produce novel antibodies for immunotherapy.

Organ growth, regeneration and aging: A focus on the vascular system.

Developing new tools for human MRI, especially at ultra-high field 7T MRI scanner, aiming to better understand the human brain function

We are interested in deciphering questions spanning from molecular to behavioral levels

Intracellular and intercellular trafficking of mRNA and its role in protein localization and cell physiology

Studying how human organs acquire their shape by developing 3D stem-cell systems and applying concepts from soft-matter physics