Protein Purification Publications

  1. Giannoulis A., Feintuch A., Barak Y., Mazal H., Albeck S., Unger T., Yang F., Su X. & Goldfarb D. (2020). Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques.  Proceedings of the National Academy of Sciences of the United States of America. 2020 Jan 7 , 117 (1):395-404.
  2. Gabizon R., Shraga A., Gehrtz P., Livnah E., Shorer Y., Gurwicz N., Avram L., Unger T., Aharoni H., Albeck S., Brandis A., Shulman Z., Katz B., Herishanu Y. & London N. (2020). Efficient targeted degradation via reversible and irreversible covalent PROTACs.  Journal of the American Chemical Society. 2020 Jul 8 , 142 (27):11734-11742.
  3. Davidi D., Shamshoum M., Guo Z., BarOn Y. M., Prywes N., Oz A., Jablonska J., Flamholz A., Wernick D. G., Antonovsky N., Pins B., Shachar L., Hochhauser D., Peleg Y., Albeck S., Sharon I., MuellerCajar O. & Milo R. (2020). Highly active rubiscos discovered by systematic interrogation of natural sequence diversity.  The EMBO Journal. 2020 Sept 15 , 39 (18).
  4. Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Nissan G. B., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J. (2020). Erratum: Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces (PLoS Computational Biology(2019)15: 8(e1007207)Doi: 10.1371/journal.pcbi.1007207).  PLoS Computational Biology. 2020 Oct 21 , 16 (10).
  5. Dalaloyan A., Martorana A., Barak Y., Gataulin D., Reuveny E., Howe A., Elbaum M., Albeck S., Unger T., Frydman V., Abdelkader E. H., Otting G. & Goldfarb D. (2019). Tracking Conformational Changes in Calmodulin in vitro, in Cell Extract, and in Cells by Electron Paramagnetic Resonance Distance Measurements.  ChemPhysChem. 2019 Jul 16 , 20 (14):1860-1868.
  6. Shraga A., Olshvang E., Davidzohn N., Khoshkenar P., Germain N., Shurrush K., Carvalho S., Avram L., Albeck S., Unger T., Lefker B., Subramanyam C., Hudkins R. L., Mitchell A., Shulman Z., Kinoshita T. & London N. (2019). Covalent Docking Identifies a Potent and Selective MKK7 Inhibitor.  Cell Chemical Biology. 2019 Jan 17 , 26 (1):98 - 108.
  7. Warszawski S., Katz A. B., Lipsh R., Khmelnitsky L., Ben Nissan G., Javitt G., Dym O., Unger T., Knop O., Albeck S., Diskin R., Fass D., Sharon M. & Fleishman S. J. (2019). Optimizing antibody affinity and stability by the automated design of the variable light-heavy chain interfaces.  PLoS Computational Biology. 2019 Aug 23 , 15 (8).
  8. Baron S., Peleg Y., Grunwald J., Morgenstern D., Elad N., Peretz M., Albeck S., Levin Y., Welch J. T., DeWeerd K. A., Schwarz A., Burstein Y., Diskin R., Shakked Z. & Zimhony O. (2018). Expression of a recombinant, 4'-Phosphopantetheinylated, active M. tuberculosis fatty acid synthase I in E. coli.  PLoS ONE. 2018 Sept 24 , (9).
  9. Netzer R., Listov D., Lipsh R., Dym O., Albeck S., Knop O., Kleanthous C. & Fleishman S. J. (2018). Ultrahigh specificity in a network of computationally designed protein-interaction pairs.  Nature Communications. 2018 Dec 11 , 9 (1).
  10. Elad N., Baron S., Peleg Y., Albeck S., Grunwald J., Raviv G., Shakked Z., Zimhony O. & Diskin R. (2018). Structure of Type-I Mycobacterium tuberculosis fatty acid synthase at 3.3 angstrom resolution.  Nature Communications. 2018 Sept 24 , 9 (1).
  11. Kantaev R., Riven I., Goldenzweig A., Barak Y., Dym O., Peleg Y., Albeck S., Fleishman S. J. & Haran G. (2018). Manipulating the Folding Landscape of a Multi-Domain Protein.  Journal of Physical Chemistry B. 2018 Dec 13 , 122 (49):11030-11038.
  12. Lapidoth G., Khersonsky O., Lipsh R., Dym O., Albeck S., Rogotner S. & Fleishman S. J. (2018). Highly active enzymes by automated combinatorial backbone assembly and sequence design.  Nature Communications. 2018 Jul 17 , 9 .
  13. Erez Z., Steinberger-Levy I., Shamir M., Doron S., Stokar Avihail A. A., Peleg Y., Melamed S., Leavitt A., Savidor A., Albeck S., Amitai G. & Sorek R. (2017). Communication between viruses guides lysis-lysogeny decisions.  Nature. 2017 Jan 26 , 541 (7638):488-493.
  14. Baran D., Pszolla M. G., Lapidoth G. D., Norn C., Dym O., Unger T., Albeck S., Tyka M. D. & Fleishman S. J. (2017). Principles for computational design of binding antibodies.  Proceedings of the National Academy of Sciences of the United States of America. 2017 Oct 10 , 114 (41):10900-10905.
  15. Goldenzweig A., Goldsmith M., Hill S. E., Gertman O., Laurino P., Ashani Y., Dym O., Unger T., Albeck S., Prilusky J., Lieberman R. L., Aharoni A., Silman I., Sussman J., Tawfik D. & Fleishman S. J. (2016). Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability.  Molecular Cell. 2016 Jul 21 , 63 (2):337-346.
  16. Zimhony O., Schwarz A., Raitses-Gurevich M., Peleg Y., Dym O., Albeck S., Burstein Y. & Shakked Z. (2015). AcpM, the meromycolate extension Acyl carrier protein of mycobacterium tuberculosis, is activated by the 4-phosphopantetheinyl transferase PptT, a potential target of the multistep mycolic acid biosynthesis.  Biochemistry. 2015 Apr 14 , 54 (14):2360-2371.
  17. Nissinkorn Y., Lahav-Mankovski N., Rabinkov A., Albeck S., Motiei L. & Margulies D. (2015). Sensing Protein Surfaces with Targeted Fluorescent Receptors.  Chemistry - A European Journal. 2015 Nov 1 , 21 (45):15981-15987.
  18. Sun L., Xiong Y., Bashan A., Zimmerman E., Daube S. S., Peleg Y., Albeck S., Unger T., Yonath H., Krupkin M., Matzov D. & Yonath A. (2015). A Recombinant Collagen-mRNA Platform for Controllable Protein Synthesis.  ChemBioChem. 2015 Jul 6 , 16 (10):1415-1419.
  19. Krieg E., Albeck S., Weissman H., Shimoni E. & Rybtchinski B. (2013). Separation, Immobilization, and Biocatalytic Utilization of Proteins by a Supramolecular Membrane.  PLoS ONE. 2013 May 10 , 8 (5).
  20. Bharat T. A. M., Zbaida D., Eisenstein M., Frankenstein Z., Mehlman T., Weiner L., Sorzano C. O. S., Barak Y., Albeck S., Briggs J. A. G., Wolf S. G. & Elbaum M. (2013). Variable internal flexibility characterizes the helical capsid formed by agrobacterium VirE2 protein on single-stranded DNA.  Structure. 2013 Jul 2 , 21 (7):1158-1167.