Electron Microscopy

4D STEM involves acquiring a 2D convergent beam electron diffraction (CBED) pattern, at every pixel of a 2D STEM raster, generating a 4D dataset containing momentum and spatial information about the specimen. The key advantage of 4D STEM compared to conventional 2D STEM imaging…

Recent advances in fabrication of MEMS devices have renewed interest to reveal dynamic processes in materials with high spatial and temporal resolution in the TEM. Transformations in liquid and gaseous environment, upon heating or biasing, enable for instance the investigation of…

Cryogenic transmission electron microscopy is conducted on specimens that are cooled in the microscope. Cryogenic  observation, such as at liquid nitrogen temperature, improves the stability of the material or allows for observing a material whose properties change at lower…

Tomography aims at the reconstruction of the three-dimensional structure of a sample from two dimensional representations. The most common form of tomography in materials science is the reconstruction from a set of images of a single object taken under various viewing directions…

X-ray tomography is ideally suitable for non-destructive three-dimensional visualization and analysis of a wide range of samples, from biological tissues to synthetic materials. Tomographic datasets are obtained by imaging a rotating sample positioned between an X-ray source and…

Many biological insights can be obtained by combining the power of Fluorescence Microscopy with that of Electron Microscopy to study the same sample – this is called Correlative Light and Electron Microscopy (CLEM).

In Fluorescence Microscopy, specific biological entities can…

Many biological insights can be obtained by combining the power of Fluorescence Microscopy with that of Electron Microscopy to study the same sample – this is called Correlative Light and Electron Microscopy (CLEM).

In Fluorescence Microscopy, specific biological entities can…

Fluorescence microscopy is one of the most versatile imaging method in biology. However, the resolution of a conventional wide-field fluorescence microscope is limited by the diffraction of light to several hundred nanometers. Stochastic optical reconstruction microscopy (STORM)…